Asymmetric Elongation of Foveal Tissue after Macular Hole Surgery and Its Impact on Metamorphopsia

Asymmetric Elongation of Foveal Tissue after Macular Hole Surgery and Its Impact on Metamorphopsia
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DOI:
10.1016/j.ophtha.2012.05.018
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发表时间:
2012-10-01
期刊:
影响因子:
13.7
通讯作者:
Ha, Hyo Shin
Ha, Hyo Shin
中科院分区:
医学1区
文献类型:
--
作者:
Kim, Jae Hui;Kang, Se Woong;Ha, Hyo Shin

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目的:评估黄斑裂孔(MH)手术后黄斑中心凹组织的延长情况,并研究其对视功能的影响。设计:前瞻性,干预性病例系列。参与者:来自31名因直径小于400 μ m的MH接受手术的患者的31只眼。方法:外丛状层(OPL)的翼旁边缘之间的距离被定义为OPL距离,并在术后首次访视以及术后2个月和6个月访视时根据光学相干断层扫描图像进行测量。中心凹组织在某些方向上的进一步伸长被定义为不对称伸长。评估了平均不对称延长程度与视力和视物变形评分(M-评分)结局的相关性。主要结局指标:OPL间距离和M-评分。在规定的时间点测量的水平OPL间距离分别为361.6 +/- 99.6 μ m、558.8 +/- 93.3 μ m和575.4 +/- 94.8 μ m。OPL间垂直距离分别为324.2 +/- 93.8 μ m、481.2 +/- 104.6 μ m和494.6 +/- 85.0 μ m。随访期间OPL水平和垂直间距均增加(P
Purpose: To evaluate the elongation profile of foveal tissue after macular hole (MH) surgery and to investigate its impact on visual function.Design: Prospective, interventional case series.Participants: Thirty-one eyes from 31 patients who underwent surgery for an MH less than 400 mu m in diameter.Methods: The distance between the parafoveal edge of the outer plexiform layer (OPL) was defined as the inter-OPL distance and measured on the basis of optical coherence tomography images at the first postoperative visit and the 2- and 6-month postoperative visits. Further elongation of the foveal tissue in certain directions was defined as asymmetric elongation. The association of the mean degree of asymmetric elongation with visual acuity and metamorphopsia score (M-score) outcome was evaluated.Main Outcome Measures: Inter-OPL distance and M-score.Results: Macular hole sealing was noted in all eyes after surgery. The horizontal inter-OPL distances measured at the defined time points were 361.6 +/- 99.6 mu m, 558.8 +/- 93.3 mu m, and 575.4 +/- 94.8 mu m, respectively. The vertical inter-OPL distances were 324.2 +/- 93.8 mu m, 481.2 +/- 104.6 mu m, and 494.6 +/- 85.0 mu m, respectively. Both the horizontal and vertical inter-OPL distances were increased during the follow-up period (P