Prognostic Value of Labyrinthine 3D-FLAIR Abnormalities in Idiopathic Sudden Sensorineural Hearing Loss
Prognostic Value of Labyrinthine 3D-FLAIR Abnormalities in Idiopathic Sudden Sensorineural Hearing Loss
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DOI：
10.3174/ajnr.a4901
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发表时间：
2016-12-01
影响因子：
3.5
通讯作者：
Park, H. J.
中科院分区：
文献类型：
--
作者：
Lee, J. L.;Yoon, R. G.;Park, H. J.
背景和目的：根据最近的研究，现代磁共振成像可以检测迷路是否存在异常。我们的目的是报告突发感音神经性听力损失患者迷路成像异常结果的模式和预后作用。 材料和方法：本研究包括 113 名被诊断为单侧突发感音神经性听力损失并接受 3T MR 成像的患者，包括对比前/对比后 3D 液体衰减反转恢复和 TI 加权成像。我们分析了 MR 成像的异常情况，并将其与听力测试结果相关联。结果：31 名 (27%) 患者在受累耳朵的迷路 MR 成像中显示出异常结果。 MRI+ 组的初始/最终听力水平（91 +/- 25/73 +/- 27 dB 听力损失）明显低于 MRI- 组（69 +/- 30/48 +/- 24 dB 听力损失）。 40 名初始轻度至中度听力损失的患者中，迷路 MR 成像异常发生率（40 名中的 3 名，8%）显着低于重度听力损失患者（34 名中的 16 名，47%）。考虑到 Siegel 标准的听力改善，MRI- 组的完全或部分恢复率 (34%) 显着高于 MRI+ 组 (10%)。在最初出现严重或极重度听力损失的患者中，MRI- 组的听力改善程度 (38 +/- 21 dB) 高于 MRI+ 组 (23 +/- 22 dB)。结论：27% 的突发感音神经性听力损失患者发现迷路 MR 成像异常。 MRI+ 组的初始听力记录比 MRI- 组更差。对于最初患有严重和深度听力损失的患者，迷路 MR 成像异常表明预后不良。
BACKGROUND AND PURPOSE: According to recent research, modern MR imaging can detect the presense of abnormalities on labyrinthine. Our aim was to report the patterns and prognostic role of abnormal findings on labyrinthine imaging in patients with sudden sensorineural hearing loss.MATERIALS AND METHODS: This study comprised 113 patients who were diagnosed with unilateral sudden sensorineural hearing loss and underwent 3T MR imaging, including pre-/postcontrast 3D fluid-attenuated inversion recovery and TI-weighted imaging. We analyzed abnormalities on MR imaging and correlated them with audiometric results.RESULTS: Thirty-one (27%) patients showed abnormal findings on labyrinthine MR imaging in the affected ear. The initial/final hearing levels of the MRI+ group (91 +/- 25/73 +/- 27 dB hearing loss) were significantly worse than those of the MRI- group (69 +/- 30/48 +/- 24 dB hearing loss). The incidence of abnormalities on labyrinthine MR imaging was significantly lower (3 of 40, 8%) in 40 patients with initial mild-to-moderate hearing loss than in those with profound hearing loss (16 of 34, 47%). Considering hearing improvement by the Siegel criteria, the rate of complete or partial recovery was significantly higher in the MRI- group (34%) than in the MRI+ group (10%). In patients with initial severe or profound hearing loss, the MRI- group showed greater hearing improvement (38 +/- 21 dB) than the MRI+ group (23 +/- 22 dB).CONCLUSIONS: Abnormalities on labyrinthine MR imaging were found in 27% of patients with sudden sensorineural hearing loss. The initial hearing logs was worse in the MRI+ group than in the MRI- group. In patients with initial severe and profound hearing loss, the presence of abnormalities on labyrinthine MR imaging indicated a poor prognosis.