Diamond microelectrodes for in vitro electroanalytical measurements:: current status and remaining challenges
Diamond microelectrodes for in vitro electroanalytical measurements:: current status and remaining challenges
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DOI：
10.1039/b710236b
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发表时间：
2008-01-01
期刊：
影响因子：
4.2
通讯作者：
Swain, Greg M.
中科院分区：
文献类型：
--
作者：
Park, Jinwoo;Quaiserova-Mocko, Veronika;Swain, Greg M.
当今电化学领域的一个新兴研究领域是金刚石微电极的制备、表征和应用，用于生物介质的电分析测量。对这种新型电极材料的兴趣源于其卓越的特性：(i)硬度，（ii）低，稳定和不依赖ph的背景电流，（iii）在广泛的电位范围内具有形态和微观结构稳定性，（iv）对多种氧化还原分析物具有良好的电化学响应性，无需任何常规预处理，(v)极性分子的弱分子吸附导致高水平的抵抗响应失活和电极污染。近年来，金刚石电极已经从单纯的科学好奇心发展成为一种可行的电分析材料。在本文中，我们重点介绍了我们实验室和其他实验室在这种新型微电极的制备、基本电化学性质的研究以及在体外电分析测量中的应用方面的进展情况，并讨论了一些仍然存在的挑战。
An emerging research field in electrochemistry today is the preparation, characterization and application of diamond microelectrodes for electroanalytical measurements in biological media. Interest in this new electrode material stems from its outstanding properties: (i) hardness, (ii) low, stable and pH-independent background current, (iii) morphological and microstructural stability over a wide range of potentials, (iv) good electrochemical responsiveness for multiple redox analytes without any conventional pre-treatment and (v) weak molecular adsorption of polar molecules that leads to a high level of resistance to response deactivation and electrode fouling. Diamond electrodes have advanced in recent years from being simply a scientific curiosity into a viable material for electroanalysis. In this article, we highlight the current state of progress by our laboratory and others on the preparation, study of the basic electrochemical properties, and application of this new type of microelectrode for in vitro electroanalytical measurements, and discuss some of the remaining challenges.