A method of reporting macular edema after cataract surgery using optical coherence tomography
A method of reporting macular edema after cataract surgery using optical coherence tomography
复制标题
DOI：
10.1097/iae.0b013e318169d04e
复制
发表时间：
2008-06-01
影响因子：
3.3
通讯作者：
Jabs, Douglas A.
中科院分区：
文献类型：
--
作者：
Kim, Stephen J.;Belair, Marie-Lyne;Jabs, Douglas A.
目的：目的：探讨光学相干断层扫描（OCT）在白内障术后黄斑水肿（ME）诊断中的应用价值。每只眼睛在术前4周内以及术后1个月和3个月接受OCT检查。结果：ME的发生率为14%（95%可信区间，8-20）。在1个月时，有和无ME的眼睛的基线中心点厚度（CPT）+/- SD的平均增加分别为202 +/- 113 μ m和8 +/- 19 μ m（P < 0.001），导致1个字母丢失（-0.02 logMAR [最小分辨角的对数]）和3线视力增益（0.29 logMAR）（P < 0.001）。有和无ME的眼睛基线CPT +/- SD的百分比变化分别为115 +/- 67%和6 +/-11%（P < 0.001）。基线CPT增加>= 40%准确地确定了100%的ME眼和99%的无ME眼。结论：OCT确定的基线CPT增加>= 40%，提供了一种有效和客观的方法来报告临床相关的白内障后ME。白内障后ME的标准化报告将允许客观评估和比较临床研究中的治疗结果。
Objective: To validate a method of reporting postcataract macular edema (ME) using optical coherence tomography (OCT).Methods: Data were analyzed for 130 eyes followed prospectively for ME after uncomplicated cataract surgery. Each eye underwent OCT within 4 weeks before surgery and at 1 month and 3 months after surgery. ME was defined by observation of cystoid changes by OCT.Results: Incidence of ME was 14% (95% confidence interval, 8-20). Average increase in baseline center point thickness (CPT) +/- SD at 1 month for eyes with and without ME was 202 +/- 113 mu m and 8 +/- 19 mu m, respectively (P < 0.001), which resulted in a 1-letter loss (-0.02 logMAR [logarithm of the minimum angle of resolution]) and a 3-line gain (0.29 logMAR) in vision, respectively (P < 0.001). Percent change in baseline CPT +/- SD for eyes with and without ME was 115 +/- 67% and 6 +/- 11%, respectively (P < 0.001). A >= 40% increase in baseline CPT accurately determined 100% of eyes with ME and 99% of eyes without ME.Conclusions: A >= 40% increase in baseline CPT, determined by OCT, offers a valid and objective method of reporting clinically relevant postcataract ME. Standardized reporting of postcataract ME would allow objective assessment and comparison of treatment outcomes among clinical studies.