Bone resorption inhibitors from hop extract
Bone resorption inhibitors from hop extract
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DOI：
10.1271/bbb.61.158
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发表时间：
1997-01-01
影响因子：
1.6
通讯作者：
Nagai, M
中科院分区：
文献类型：
--
作者：
Tobe, H;Muraki, Y;Nagai, M
我们在啤酒花提取物中寻找抑制骨吸收的活性成分，并分离出黄腐酚和蛇麻酮作为活性成分，特别是蛇麻酮具有非常强的抑制活性，IC 50（50%抑制浓度）值为5.9 × 10（-9）M。
We searched hop extract for active component(s) that inhibited bone resorption in the pit formation assay, and isolated xanthohumol and humulone as active ingredients, Especially humulone had extraordinarily strong inhibitory activity and the IC50 (concentration of 50% inhibition) value was 5.9 x 10(-9) M.