Remineralization of enamel caries can decrease optical reflectivity
Remineralization of enamel caries can decrease optical reflectivity
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DOI：
10.1177/154405910608500905
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发表时间：
2006-09-01
影响因子：
7.6
通讯作者：
Fried, D.
中科院分区：
文献类型：
--
作者：
Jones, R. S.;Fried, D.
牙釉质龋齿的再矿化可导致病变内明显的光学变化。我们假设，矿物体积的恢复将导致病变偏振光的深度分辨反射率明显下降。为了验证这一假设，我们使用偏振敏感光学相干断层扫描(PS-OCT)测量了人工龋齿再矿化过程中的光学变化作为深度的函数。在暴露于再矿化方案之前和之后，非破坏性地对病变进行成像。成像后，组织学薄片的显微放射照片表明，PS-OCT测量的显著反射率降低准确地反映了较大修复表面区内矿物含量的增加。再矿化引起的矿物质体积变化可以根据病变的光学反射率来测量。
The remineralization of enamel caries can lead to distinct optical changes within a lesion. We hypothesized that the restoration of mineral volume would result in a measurable decrease in the depth-resolved reflectivity of polarized light from the lesion. To test this hypothesis, we measured optical changes in artificial caries undergoing remineralization as a function of depth, using Polarization-sensitive Optical Coherence Tomography (PS-OCT). Lesions were imaged non-destructively before and after exposure to a remineralization regimen. After imaging, microradiographs of histological thin sections indicated that the significant reflectivity reduction measured by PS-OCT accurately represented the increase in mineral content within a larger repaired surface zone. Mineral volume changes arising from remineralization can be measured on the basis of the optical reflectivity of the lesion.