A randomized-controlled trial of an early minimal cognitive-behavioural therapy for insomnia comorbid with cancer
A randomized-controlled trial of an early minimal cognitive-behavioural therapy for insomnia comorbid with cancer
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DOI：
10.1016/j.brat.2015.02.003
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发表时间：
2015-04-01
影响因子：
4.1
通讯作者：
Savard, Marie-Helene
中科院分区：
文献类型：
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作者：
Casault, Lucie;Savard, Josee;Savard, Marie-Helene
目的：本研究旨在为早期最小认知行为疗法治疗癌症合并急性失眠 (mCBT-I) 的疗效提供初步证据。 方法：38 名患有各种类型癌症且失眠症状少于 6 个月的患者（92% 为女性；57 岁中年；均为白种人）被随机分配至自行给药组 mCBT-I 状况（n = 20；6 本小册子 + 3 次心理学家电话咨询，超过 6 周）或不治疗状况（n = 18）。在治疗前和治疗后以及3个月和6个月的随访时完成测量。结果：治疗参与者的所有睡眠参数和安眠药的平均剂量从治疗前到治疗后均显着改善，但对照组参与者没有。 mCBT-I 还可以显着减少焦虑和抑郁症状、适应不良的睡眠习惯和对睡眠的错误信念，并显着改善主观认知功能。与对照组相比，mCBT-I 参与者中符合治疗后临床缓解标准的比例更高。 mCBT-I 的治疗效果在干预后可以很好地维持长达 6 个月。结论：本研究支持早期最小 CBT-I 治疗癌症合并急性失眠的功效。 (C) 2015 Elsevier Ltd. 保留所有权利。
Objective: This study aimed to provide preliminary evidence on the efficacy of an early minimal cognitive-behavioural therapy for acute insomnia (mCBT-I) comorbid with cancer.Method: Thirty-eight patients (92% female; M-age 57; all Caucasian) with various types of cancer and having insomnia symptoms for less than 6 months were randomized to a self-administered mCBT-I condition (n = 20; 6 short booklets + 3 phone consultations with a psychologist, over 6 weeks) or a no-treatment condition (n = 18). Measures were completed at pre-treatment and post-treatment, as well as at 3- and 6-month follow-ups.Results: All sleep parameters and the average dosage of hypnotics were significantly improved from pre- to post-treatment among treated participants, but not in control participants. mCBT-I was also associated with a significantly greater reduction of anxiety and depression symptoms, maladaptive sleep habits, and erroneous beliefs about sleep, as well as with a significantly greater improvement of subjective cognitive functioning. A greater proportion of mCBT-I participants than controls met the criteria for a clinical remission at post-treatment. Therapeutic gains of mCBT-I were well sustained up to 6 months after the intervention.Conclusions: This study supports the efficacy of an early minimal CBT-I to treat acute insomnia comorbid with cancer. (C) 2015 Elsevier Ltd. All rights reserved.