Ultra-high-resolution computed tomography can demonstrate alveolar collapse in novel coronavirus (COVID-19) pneumonia
Ultra-high-resolution computed tomography can demonstrate alveolar collapse in novel coronavirus (COVID-19) pneumonia
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DOI：
10.1007/s11604-020-00956-y
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发表时间：
2020-03-31
影响因子：
2.1
通讯作者：
Ogura, Takashi
中科院分区：
文献类型：
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作者：
Iwasawa, Tae;Sato, Midori;Ogura, Takashi
目的探讨新型冠状病毒病新冠肺炎患者的胸部超高分辨率CT表现。材料与方法2020年2月，连续6例新冠肺炎肺炎患者(中位年龄69岁)行U-HRCT扫描。U-HR-CT矩阵大小为1024×1024，薄层厚度为0.25 mm，可显示正常肺的末梢细支气管区，可显示Reid‘s次级小叶及其异常。由两位经验丰富的评价者在1K监视器上对U-HRCT上肺内阴影的分布和特征(磨玻璃样阴影、实变伴或不伴结构扭曲、线状阴影、疯狂铺路)进行直观评估。测量CT肺体积，计算基于性别、年龄和身高的测得肺体积与预计总肺活量的比率(PredTLC)。结果所有病例在U-HRCT上均表现为疯狂铺路。在这些病变中，次级小叶比未受影响的肺小。与predTLC相比，2例患者的CT肺体积减小。结论高分辨率CT不仅能评价新冠肺炎肺炎的分布和征象，还能显示局部肺容量丢失。
Purpose To review the chest computed tomography (CT) findings on the ultra-high-resolution CT (U-HRCT) in patients with the Novel coronavirus disease 2019 (COVID-19). Materials and Methods In February 2020, six consecutive patients with COVID-19 pneumonia (median age, 69 years) underwent U-HR CT imaging. U-HR-CT has a larger matrix size of 1024 x 1024 thinner slice thickness of 0.25 mm and can demonstrate terminal bronchioles in the normal lungs; as a result, Reid's secondary lobules and their abnormalities can be identified. The distribution and hallmarks (ground-glass opacity, consolidation with or without architectural distortion, linear opacity, crazy paving) of the lung opacities on U-HRCT were visually evaluated on a 1 K monitor by two experienced reviewers. The CT lung volume was measured, and the ratio of the measured lung volume to the predicted total lung capacity (predTLC) based on sex, age and height was calculated. Results All cases showed crazy paving pattern in U-HRCT. In these lesions, the secondary lobules were smaller than those in the un-affected lungs. CT lung volume decreased in two cases comparing predTLC. Conclusion U-HRCT can evaluate not only the distribution and hallmarks of COVID-19 pneumonia but also visualize local lung volume loss.