Higher plant RecA-like protein is homologous to RadA
Higher plant RecA-like protein is homologous to RadA
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DOI：
10.1016/j.dnarep.2005.07.010
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发表时间：
2006-01-05
期刊：
影响因子：
3.8
通讯作者：
Sakaguchi, K
中科院分区：
文献类型：
--
作者：
Ishibashi, T;Isogai, M;Sakaguchi, K
A novel RecA-like protein, differing from Dmc1 and Rad51, was characterized in Oryza sativa L. cv. Nipponbare. Because the protein is homologous to bacterial RadA, the gene was designated OsRadA. The open reading frame was predicted to encode a 66 kDa protein of 619 amino acid residues and was found in plants but not animals or yeast. OsRadA showed D-loop and single-stranded DNA-dependent ATPase activities. Gene expression was found to be high in meristematic tissues, and was localized in the nucleus. An RNAi mutant of Arabidopsis thaliana RadA (AtRadA) was sensitive to mutagenic agents such as UV and MMC, suggesting that RadA functions in DNA repair. (C) 2005 Elsevier B.V. All rights reserved.
