Automated detection of the intercommissural line for stereotactic localization of functional brain images.
Automated detection of the intercommissural line for stereotactic localization of functional brain images.
复制标题
自动检测连合间线，用于功能性脑图像的立体定向定位。
DOI：
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发表时间：
1993
影响因子：
9.3
通讯作者：
David E. Kuhl
中科院分区：
文献类型：
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作者：
S. Minoshima;R. Koeppe;M. Mintun;Keven L. Berger;S. Taylor;K. Frey;K. Frey;David E. Kuhl
一种用于正电子发射断层扫描（PET）的连合间（AC-PC）线自动检测的技术已经开发出来。AC-PC线是根据四个内部标志的位置来估计的：额极和枕极、胼胝体前部的下方和丘脑底点。结合边缘检测、插值和轮廓曲线分析技术，在PET正中矢状切片中自动检测标志点。通过磁共振（MR）图像分析证实了标志的真实AC-PC线和估计AC-PC线之间的解剖关系。在共配准的PET和MR图像中评估了自动估计技术的准确性，其显示了从真实AC-PC线估计的最小角度差异和位移。PET研究中AC-PC线的自动检测可实现功能信号的准确立体定位，而无需额外的解剖成像，并为客观和可重现的受试者间比较提供了基础。
A technique has been developed for automated detection of the intercommissural (AC-PC) line for positron emission tomography (PET). The AC-PC line is estimated from the location of four internal landmarks; the frontal and occipital poles, the inferior aspect of the anterior corpus callosum, and the subthalamic point. The landmarks are detected automatically in PET mid-sagittal slices by combining edge detection, interpolation and profile curve analysis techniques. The anatomical relationships between the true and estimated AC-PC lines from the landmarks was confirmed by analysis of magnetic resonance (MR) images. Accuracy of the automated estimation technique was assessed in co-registered PET and MR images, which showed minimal angular differences and displacements of the estimated from the true AC-PC lines. The automated detection of the AC-PC line in a PET study enables accurate stereotactic localization of functional signals without the need for additional anatomical imaging and provides a basis for objective and reproducible intersubject comparison.