A pregnancy and postpartum lifestyle intervention in women with gestational diabetes mellitus reduces diabetes risk factors: a feasibility randomized control trial.

A pregnancy and postpartum lifestyle intervention in women with gestational diabetes mellitus reduces diabetes risk factors: a feasibility randomized control trial.
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DOI:
10.2337/dc10-2221
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发表时间:
2011-07
期刊:
影响因子:
16.2
通讯作者:
Crites Y
Crites Y
中科院分区:
医学1区
文献类型:
--
作者:
Ferrara A;Hedderson MM;Albright CL;Ehrlich SF;Quesenberry CP Jr;Peng T;Feng J;Ching J;Crites Y

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在妊娠期糖尿病(GDM)妇女中,试验产前/产后干预的可行性,以改变饮食和体力活动,类似于糖尿病预防计划。通过电话进行干预,并解决了对母乳喂养的支持问题。其目标是帮助妇女恢复到孕前体重,如果是正常的,或实现从孕前体重减少5%,如果超重。符合条件的参与者在GDM诊断后不久被确定; 83.8%的人同意被随机分配到干预或常规医疗护理(分别为96和101名妇女)。产后12个月时保留率为85.2%。在干预条件下,达到产后体重目标的妇女比例高于常规护理(37.5% vs. 21.4%,绝对差异16.1%,P = 0.07),但无统计学显著性。干预措施在未超过推荐妊娠期体重增加的妇女中更有效(达到体重目标的妇女比例差异:22.5%,P = 0.04)。干预条件比常规护理更多地减少了膳食脂肪摄入量(来自脂肪的卡路里百分比平均变化的条件差异:-3.6%,P = 0.002),并增加了母乳喂养,尽管不显著(比例条件差异:15.0%,P = 0.09)。产后体力活动没有差异,观察条件之间。这项研究表明,从怀孕期间开始并在产后继续进行的生活方式干预是可行的,可以防止怀孕体重保持并帮助超重妇女减肥。帮助产后妇女克服增加身体活动的障碍的策略是必要的。
To pilot, among women with gestational diabetes mellitus (GDM), the feasibility of a prenatal/postpartum intervention to modify diet and physical activity similar to the Diabetes Prevention Program. The intervention was delivered by telephone, and support for breastfeeding was addressed. The goal was to help women return to their prepregnancy weight, if it was normal, or achieve a 5% reduction from prepregnancy weight if overweight. Eligible participants were identified shortly after a GDM diagnosis; 83.8% consented to be randomly assigned to intervention or usual medical care (96 and 101 women, respectively). The retention was 85.2% at 12 months postpartum. The proportion of women who reached the postpartum weight goal was higher, although not statistically significant, in the intervention condition than among usual care (37.5 vs. 21.4%, absolute difference 16.1%, P = 0.07). The intervention was more effective among women who did not exceed the recommended gestational weight gain (difference in the proportion of women meeting the weight goals: 22.5%, P = 0.04). The intervention condition decreased dietary fat intake more than the usual care (condition difference in the mean change in percent of calories from fat: −3.6%, P = 0.002) and increased breastfeeding, although not significantly (condition difference in proportion: 15.0%, P = 0.09). No differences in postpartum physical activity were observed between conditions. This study suggests that a lifestyle intervention that starts during pregnancy and continues postpartum is feasible and may prevent pregnancy weight retention and help overweight women lose weight. Strategies to help postpartum women overcome barriers to increasing physical activity are needed.
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