EFFECTS OF ESTROGENIC COMPOUNDS ON TRIGLYCERIDE KINETICS
EFFECTS OF ESTROGENIC COMPOUNDS ON TRIGLYCERIDE KINETICS
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DOI：
10.1016/0026-0495(75)90078-5
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发表时间：
1975-01-01
影响因子：
9.8
通讯作者：
SCHEEL, D
中科院分区：
文献类型：
--
作者：
GLUECK, CJ;FALLAT, RW;SCHEEL, D
Paired studies of triglyceride kinetics were made in 8 women on and off postmenopausal estrogen supplementation. When estrogens were discontinued, mean very-low-density lipoprotein triglyceride (VLD-TG) and VLD-TG turnover rate fell respectively from 555 to 349 mg 100 ml, and from 30-18 mg/kg/hr (p< 0.01). Maximal turnover rate (V max) and VLD-TG concentration at 1 2 V max (K m), were 82.4 mg/kg/hr and 704.14 mg 100 ml on estrogen and fell to 41.83 and 347.51 when estrogen was discontinued (p< 0.01). Estrogen supplementation did not lengthen VLD-TG half-life or diminish the fractional turnover rate of VLD-TG. Estrogens apparently increase VLD-TG by augmenting VLD-TG production rates.
