Properties of the stochastic energization-relaxation channel model for vectorial ion transport.
Properties of the stochastic energization-relaxation channel model for vectorial ion transport.
复制标题
矢量离子传输的随机赋能-弛豫通道模型的特性。
DOI:
10.1016/s0006-3495(00)76674-4
复制
发表时间:
2000
影响因子:
3.4
通讯作者:
T. Fukami
中科院分区:
文献类型:
--
作者:
E. Muneyuki;T. Fukami
A model for the primary active transport by an ion pump protein is proposed. The model, the "energization-relaxation channel model," describes an ion pump as a multiion channel that undergoes stochastic transitions between two conformational states by external energy supply. When the potential profile along ion transport pathway is asymmetrical, a net ion flux is induced by the transitions. In this model, the coupling of the conformational change and ion transport is stochastic and loose. The model qualitatively reproduces known properties of active transport such as the effect of ion concentration gradient and membrane potential on the rate of transport and the inhibition of ion transport at high ion concentration. We further examined the effect of various parameters on the ion transport properties of this model. The efficiency of the coupling was almost 100% under some conditions.
登录
查看更多内容
影响因子:
2.9
作者:
Richter, HT;Brown, LS;Lanyi, JK
通讯作者:
Lanyi, JK
影响因子:
56.9
作者:
Luecke, H;Schobert, B;Lanyi, JK
通讯作者:
Lanyi, JK
DOI:
10.1073/pnas.87.3.1018
发表时间:
1990
影响因子:
11.1
作者:
Otto,H;Marti,T;Holz,M;Mogi,T;Stern,LJ;Engel,F;Khorana,HG;Heyn,MP
通讯作者:
Heyn,MP
影响因子:
56.9
作者:
Luecke, H;Richter, HT;Lanyi, JK
通讯作者:
Lanyi, JK
影响因子:
56.9
作者:
SASAKI, J;BROWN, LS;LANYI, JK
通讯作者:
LANYI, JK