THE HAMILTON DEPRESSION SCALE - EVALUATION OF OBJECTIVITY USING LOGISTIC-MODELS
THE HAMILTON DEPRESSION SCALE - EVALUATION OF OBJECTIVITY USING LOGISTIC-MODELS
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DOI：
10.1111/j.1600-0447.1981.tb00676.x
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发表时间：
1981-01-01
影响因子：
6.7
通讯作者：
NAGY, A
中科院分区：
文献类型：
--
作者：
BECH, P;ALLERUP, P;NAGY, A
汉密尔顿抑郁量表（HDS）作为抑郁状态严重程度的衡量标准的一致性进行了检查时，每周使用的规模与丙咪嗪的试验。通过使用logistic模型（Rasch），HDS的一致性被认为是在患者变量，如年龄，性别，丙咪嗪的血浆水平和诊断。最初的17项HDS缺乏足够的一致性，即，项目样本的总分不是抑郁状态的一维测量。HDS的一个抑郁子量表包含的项目总数可用于定量比较患者，尽管在某些分析中这些项目显示天花板效应。抑郁症子量表（包含抑郁情绪、内疚、工作和兴趣、迟钝、精神焦虑和一般躯体症状）可以形成进一步改进抑郁状态定量评定量表领域的基础。
The consistency of the Hamilton Depression Scale (HDS) as a measure of the severity of depressive states was examined when the scale was used weekly during a trial with imipramine. By use of logistic models (Rasch), the consistency of the HDS was considered across patient-variables as age, sex, plasma levels of imipramine and diagnosis. The original 17-item HDS was without adequate consistency, i.e., the total score of the sample of items was no 1-dimensional measure of depressive states. A melancholia subscale of the HDS contained items the total of which can be used to compare patients quantitatively, although in some part of the analysis these items showed ceiling effect. The melancholia subscale (containing the items depressed mood, guilt, work and interests, retardation, psychia anxiety and general somatic symptoms) can form the basis for further improvements in the field of quantitative rating scales for depressive states.