2dx -: User-friendly image processing for 2D crystals

2dx -: User-friendly image processing for 2D crystals
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DOI:
10.1016/j.jsb.2006.07.020
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发表时间:
2007-01-01
影响因子:
3
通讯作者:
Stahlberg, Henning
Stahlberg, Henning
中科院分区:
生物学3区
文献类型:
--
作者:
Gipson, Bryant;Zeng, Xiangyan;Stahlberg, Henning

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电子晶体学确定了二维(2D)膜蛋白晶体和其他2D晶体系统的结构。低温透射电子显微镜记录高分辨率的电子显微照片,这需要计算机处理三维结构重建。我们提出了新的软件系统2DX,这是一个用户友好的,平台无关的电子晶体学软件包。2dx帮助管理图像处理项目,指导用户完成2D晶体图像的处理,并为处理任务和结果提供支持。JavaScript以脚本模板的形式实现,让人想起c-shell脚本。这些模板可以由用户轻松修改或替换,也可以执行来自MRC软件或其他图像处理软件包的模块化独立程序。2dx在GNU通用公共许可证下可在2dx.org获得。(c)2006 Elsevier Inc. All rights reserved.
Electron crystallography determines the structure of two-dimensional (2D) membrane protein crystals and other 2D crystal systems. Cryotransmission electron microscopy records high-resolution electron micrographs, which require computer processing for three-dimensional structure reconstruction. We present anew software system 2dx, which is designed as a user-friendly, platform-independent software package for electron crystallography. 2dx assists in the management of an image-processing project, guides the user through the processing of 2D crystal images, and provides transparence for processing tasks and results. Algorithims are implemented in the form of script templates reminiscent of c-shell scripts. These templates can be easily modified or replaced by the user and can also execute modular stand-alone programs from the MRC software or from other image processing software packages. 2dx is available under the GNU General Public License at 2dx.org. (c) 2006 Elsevier Inc. All rights reserved.