EFFECT OF DETRAINING ON BONE AND MUSCLE TISSUE IN SUBJECTS WITH CHRONIC SPINAL CORD INJURY AFTER A PERIOD OF ELECTRICALLY-STIMULATED CYCLING: A SMALL COHORT STUDY
EFFECT OF DETRAINING ON BONE AND MUSCLE TISSUE IN SUBJECTS WITH CHRONIC SPINAL CORD INJURY AFTER A PERIOD OF ELECTRICALLY-STIMULATED CYCLING: A SMALL COHORT STUDY
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DOI：
10.2340/16501977-0321
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发表时间：
2009-03-01
影响因子：
3.5
通讯作者：
Eser, Prisca
中科院分区：
文献类型：
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作者：
Frotzler, Angela;Coupaud, Sylvie;Eser, Prisca
目的：探讨适应性变化的骨骼和肌肉参数在瘫痪的肢体后停止训练或减少功能性电刺激（FES）诱导的循环后，高容量的FES循环在慢性spinal cord injury.Subjects：5个主题与运动感觉完全脊髓损伤（年龄38.6岁，病变持续时间11.4年）。四名受试者在训练阶段后完全停止了FES循环，而一名受试者继续减少FES循环方法：在停止高容量FES循环后6个月和12个月，使用外周定量计算机断层扫描评估腿部的骨和肌肉参数。通过高容量FES循环在股骨远端实现的增益在停止训练一年时部分保持：大腿骨小梁骨密度占73.0%，总骨密度占63.8%，骨矿含量占59.4%，肌肉横截面积占22.1%。受试者谁继续减少FES循环保持96.2%和95.0%的总和骨小梁骨矿物质密度，和98.5%的肌肉横截面积。结论：骨和肌肉的好处实现了一年的高容量FES循环部分保存后12个月的停训，而减少循环保持骨和肌肉质量的增加。这表明，高容量的FES循环在停止训练后至少一年内具有临床意义。
Objective: To investigate adaptive changes in bone and muscle parameters in the paralysed limbs after detraining or reduced functional electrical stimulation (FES) induced cycling following high-volume FES-cycling in chronic spinal cord injury.Subjects: Five subjects with motor-sensory complete spinal cord injury (age 38.6 years, lesion duration 11.4 years) were included. Four subjects stopped FES-cycling completely after the training phase whereas one continued reduced FES-cycling (2-3 times/week, for 30 min).Methods: Bone and muscle parameters were assessed in the legs using peripheral quantitative computed tomography at 6 and 12 months after cessation of high-volume FES-cycling.Results: Gains achieved in the distal femur by high-volume FES-cycling were partly maintained at one year of detraining: 73.0% in trabecular bone mineral density, 63.8% in total bone mineral density, 59.4% in bone mineral content and 22.1% in muscle cross-sectional area in the thigh. The subject who continued reduced FES-cycling maintained 96.2% and 95.0% of the previous gain in total and trabecular bone mineral density, and 98.5% in muscle cross-sectional area.Conclusion: Bone and muscle benefits achieved by one year of high-volume FES-cycling are partly preserved after 12 months of detraining, whereas reduced cycling maintains bone and muscle mass gained. This suggests that high-volume FES-cycling has clinical relevance for at least one year after detraining.