Personal history of major depression may put women at risk for premenstrual dysphoric symptomatology.

Personal history of major depression may put women at risk for premenstrual dysphoric symptomatology.
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严重抑郁症的个人病史可能会使女性面临经前烦躁症状的风险。

DOI:
10.1016/j.jad.2013.05.091
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发表时间:
2013
影响因子:
6.6
通讯作者:
Allen,JohnJB
Allen,JohnJB
中科院分区:
医学2区
文献类型:
--
作者:
Accortt,EynavE;Kogan,AnyaV;Allen,JohnJB

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经前焦虑障碍(PMDD)是一种慢性疾病,每月都会严重影响女性的健康。虽然PMDD和重性抑郁障碍(MDD)的共同发生是常见的,大多数研究探讨PMDD的女性是否有患抑郁症的风险,而抑郁症女性的PMDD调查很少。因此,本研究探讨率PMDD在年轻抑郁women.MethodsPMDD进行了评估,使用结构化的临床访谈(SCID-PMDD)在一个样本中的164名年轻女性(n=85),没有(n=79)任何历史的depression.ResultsRates的PMDD在此样本中与MDD的妇女升高。无论参与者的MDD状态如何,这一结果都是正确的(MDD的当前、终生或仅既往病史的症状),而不管是否满足DSM-IV-TR的所有或大部分PMDD标准。限制本研究中的样本量相对较小,结论目前的研究强调临床医生需要评估年轻女性患者的PMDD,萧条经历PMDD增加的身体和心理负担的抑郁妇女可能有更严重的疾病过程,未来的研究将需要确定适当的治疗方法,为这一子集的抑郁妇女。
BackgroundPremenstrual dysphoric disorder (PMDD) is a chronic condition that significantly affects a woman's well-being on a monthly basis. Although co-occurrence of PMDD and major depressive disorder (MDD) is common, most studies examine whether women with PMDD are at risk for depression and investigations of PMDD in depressed women are scant. Therefore, the present study examined rates of PMDD in young depressed women.MethodsPMDD was assessed using a structured clinical interview (SCID-PMDD) in a sample of 164 young women with (n=85) and without (n=79) any history of depression.ResultsRates of PMDD were elevated among women with MDD in this sample. This result held true regardless of participants' MDD status (current, lifetime or past history-only symptoms of MDD) and regardless of whether all or most DSM-IV-TR PMDD criteria were met.LimitationsSample size in the present study was relatively small, and daily diary data were not available to confirm a PMDD diagnosis.ConclusionsThe current study highlights the need for clinicians to assess for PMDD in young female patients with major depression. Depressed women experiencing the added physical and psychological burden of PMDD may have a more severe disease course, and future studies will need to identify appropriate treatments for this subset of depressed women.
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