Women who abuse prescription opioids: findings from the Addiction Severity Index-Multimedia Version Connect prescription opioid database.
Women who abuse prescription opioids: findings from the Addiction Severity Index-Multimedia Version Connect prescription opioid database.
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DOI：
10.1016/j.drugalcdep.2009.03.014
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发表时间：
2009-07-01
影响因子：
4.2
通讯作者：
Butler, Stephen F.
中科院分区：
文献类型：
--
作者：
Green, Traci C.;Serrano, Jill M. Grimes;Licari, Andrea;Budman, Simon H.;Butler, Stephen F.
有证据表明处方类阿片滥用存在性别差异。本研究旨在描述寻求治疗的样本中滥用处方阿片类药物的女性的特征，并对比处方阿片类药物滥用者之间的性别差异。2005年11月至2008年4月收集的数据来自成瘾严重程度指数多媒体版本连接（ASI-MV®连接）数据库。双变量和多变量logistic回归分析了按性别分层的处方阿片类药物滥用的相关性。纳入了来自220个治疗中心的29，906项评估，其中12.8%（N= 3，821）报告了过去一个月的处方阿片类药物滥用。在过去一个月里，女性比男性更有可能报告使用任何处方阿片类药物（29.8%女性对21.1%男性，p< 0.001）和滥用任何处方阿片类药物（15.4%女性对11.1%男性，p < 0.001）。处方类阿片的给药途径和来源显示出有性别区分的趋势。近期处方阿片类药物滥用的女性特异性相关因素包括问题饮酒、年龄<54岁、吸入剂使用、居住在美国西部人口普查地区以外以及药物过量史。男性特异性相关因素为年龄<34岁、目前与子女同住、居住在南部和中西部、使用致幻剂和近期抑郁。女性处方阿片类药物滥用者不太可能报告疼痛问题，尽管她们比滥用其他药物的女性更有可能报告医疗问题。在努力筛查和确定处方类阿片滥用风险最高者时，应考虑到性别因素。有必要采取针对性别的预防和干预措施。
Evidence suggests gender differences in abuse of prescription opioids. This study aimed to describe characteristics of women who abuse prescription opioids in a treatment-seeking sample and to contrast gender differences among prescription opioid abusers. Data collected November 2005 to April 2008 derived from the Addiction Severity Index Multimedia Version Connect (ASI-MV® Connect) database. Bivariate and multivariable logistic regression examined correlates of prescription opioid abuse stratified by gender. 29,906 assessments from 220 treatment centers were included, of which 12.8% (N=3,821) reported past month prescription opioid abuse. Women were more likely than men to report use of any prescription opioid (29.8% females vs. 21.1% males, p< 0.001) and abuse of any prescription opioid (15.4% females vs. 11.1% males, p < 0.001) in the past month. Route of administration and source of prescription opioids displayed gender-specific tendencies. Women-specific correlates of recent prescription opioid abuse were problem drinking, age <54, inhalant use, residence outside of West US Census region, and history of drug overdose. Men-specific correlates were age <34, currently living with their children, residence in the South and Midwest, hallucinogen use, and recent depression. Women prescription opioid abusers were less likely to report a pain problem although they were more likely to report medical problems than women who abused other drugs. Gender-specific factors should be taken into account in efforts to screen and identify those at highest risk of prescription opioid abuse. Prevention and intervention efforts with a gender-specific approach are warranted.
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影响因子：
120.7
作者：
Hall, Aron J.;Logan, Joseph E.;Paulozzi, Leonard J.
通讯作者：
Paulozzi, Leonard J.
DOI：
10.15288/jsa.2001.62.486
发表时间：
2001-07-01
期刊：
JOURNAL OF STUDIES ON ALCOHOL
影响因子：
--
作者：
Galaif, ER;Stein, JA;Bernstein, DP
通讯作者：
Bernstein, DP
DOI：
10.1097/00005373-200001000-00018
发表时间：
2000-01-01
影响因子：
--
作者：
Gentilello, LM;Rivara, FP;Ries, RR
通讯作者：
Ries, RR
影响因子：
3.9
作者：
HENDRIKS, VM;KAPLAN, CD;GEERLINGS, P
通讯作者：
GEERLINGS, P
影响因子：
168.9
作者：
Chapman, CR;Gavrin, J
通讯作者：
Gavrin, J