Seed loss through the urinary tract after prostate brachytherapy: examining the role of cystoscopy and urine straining post implant
Seed loss through the urinary tract after prostate brachytherapy: examining the role of cystoscopy and urine straining post implant
复制标题
DOI：
10.1118/1.1604491
复制
发表时间：
2003-10-01
期刊：
影响因子：
3.8
通讯作者：
Moran, B
中科院分区：
文献类型：
--
作者：
Stutz, M;Petrikas, J;Moran, B
本研究描述了一个机构通过泌尿道进行种子回收的经验，并提出了前列腺近距离放射治疗（PB）后膀胱镜检查和尿液过滤的建议。来自两个不同时间段（早期和晚期）的不同队列的1794例患者进行了分析。所有患者预先计划采用改良的外周负荷技术，并在超声引导下植入预负荷针头（I-125或Pd-103）。在容积研究中使用导管来划定尿道，但在植入过程中没有使用。所有患者均行植入后膀胱镜检查。所有患者都被要求在植入后7天内过滤尿液，并将任何种子返回我们的中心。根据我们的经验，PB后尿路种子丢失是一种常见的事件，发生在29.7%的患者中，更常见于早期队列患者、植入I-125种子的患者或既往经尿道前列腺切除术的患者。然而，每病例的平均种子损失仅占总活性的0.58%。我们继续推荐常规植入后膀胱镜检查用于种子回收和围手术期管理。我们不再建议患者在出院后尿种失失率低的情况下在家过滤尿液。(C) 2003年美国医学物理学家协会。
This study describes one institution's experience with seed retrieval through the urinary tract and makes recommendations for cystoscopy and urine straining post prostate brachytherapy (PB). 1794 patients from two separate cohorts covering different time periods (early versus late) were analyzed. All patients were preplanned with a modified peripheral loading technique and implanted with preloaded needles (I-125 or Pd-103) under ultrasound guidance. A catheter was used to delineate the urethra during the volume study but was not used during the implant. All patients underwent post implant cystoscopy. All patients were instructed to strain their urine for seven days post implant and return any seeds to our center. In our experience, seed loss through the urinary tract is a common event after PB, occurring in 29.7% of patients and was more common in patients from the early cohort, those implanted with I-125 seeds or those patients with prior transurethral resection of the prostate. Average seed loss per case, however, represents only 0.58% of total activity. We continue to recommend routine post implant cystoscopy for seed retrieval and periprocedural management. We no longer recommend that patients strain their urine at home after documenting a low rate of seed loss after discharge. (C) 2003 American Association of Physicists in Medicine.