SARS-CoV-2 lgM/lgG antibody detection confirms the infection after three negative nucleic acid detection
SARS-CoV-2 lgM/lgG antibody detection confirms the infection after three negative nucleic acid detection
复制标题
SARS-CoV-2 lgM/lgG抗体检测 核酸检测三阴性后确诊感染
DOI：
10.1111/jcmm.15275
复制
发表时间：
2020-05-19
影响因子：
5.3
通讯作者：
Ge, Junbo
中科院分区：
文献类型：
--
作者：
Li, Hua;Pan, Jue;Ge, Junbo
2019年，新型冠状病毒在中国引发了持续的病毒性肺炎疫情。截至3月19日，全世界已报告超过20万例SARS-CoV-2感染确诊病例，超过9000例死亡。对于这一传染病，核酸检测仍是病原检测的金标准。但核酸检测耗时较长，“假阴性”相对较高;因此，我们迫切需要一种便捷、准确的检测方法来弥补这一不足。本文将介绍IgM/IgG血清抗体检测与核酸检测相比的技术特点。
An ongoing outbreak of viral pneumonia was caused by a novel coronavirus in China in 2019. By March 19, over 200 thousand confirmed cases of SARS-CoV-2 infection and over 9000 deaths have been reported throughout the world. For this infectious disease, nucleic acid detection is still the gold standard for pathogenic detection. However, nucleic acid detection takes a long time and has relatively high "false negative"; therefore, we need urgently a convenient and accurate detection method to make up for this deficiency. In this article, we will show such technical characteristics of lgM/lgG serum antibody detection, compared with nucleic acid detection.