The Interactive Effects of Estrogen and Progesterone on Changes in Emotional Eating Across the Menstrual Cycle
The Interactive Effects of Estrogen and Progesterone on Changes in Emotional Eating Across the Menstrual Cycle
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DOI：
10.1037/a0029524
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发表时间：
2013-02-01
影响因子：
4.6
通讯作者：
Hu, Jean Yueqin
中科院分区：
文献类型：
--
作者：
Klump, Kelly L.;Keel, Pamela K.;Hu, Jean Yueqin
研究表明，体内雌激素和孕激素的变化可以预测整个月经周期暴饮暴食的变化。然而，样本非常小（最大N = 9），分析没有检查激素的相互作用，这对动物摄食量的变化至关重要。本研究的目的是研究卵巢激素的相互作用，以预测迄今为止最大样本的女性（N = 196）中情绪化进食的受试者内变化。参与者提供了连续45天的情绪化饮食和唾液样本的激素测量的每日评级。结果证实，卵巢激素的变化可以预测整个月经周期中情绪性进食的变化，雌二醇与孕酮之间存在显著的相互作用。情绪化饮食评分在黄体中期最高，此时黄体酮达到峰值，雌二醇出现第二个峰值。研究结果扩展了以前的工作，强调雌激素和孕激素之间的显着相互作用，解释情绪化进食的黄体中期增加。今后的工作应探讨各种机制（例如，基因-激素相互作用），导致受试者内和受试者之间情绪化进食的差异。
Studies suggest that within-person changes in estrogen and progesterone predict changes in binge eating across the menstrual cycle. However, samples have been extremely small (maximum N = 9), and analyses have not examined the interactive effects of hormones that are critical for changes in food intake in animals. The aims of the current study were to examine ovarian hormone interactions in the prediction of within-subject changes in emotional eating in the largest sample of women to date (N = 196). Participants provided daily ratings of emotional eating and saliva samples for hormone measurement for 45 consecutive days. Results confirmed that changes in ovarian hormones predict changes in emotional eating across the menstrual cycle, with a significant estradiol x progesterone interaction. Emotional eating scores were highest during the midluteal phase, when progesterone peaks and estradiol demonstrates a secondary peak. Findings extend previous work by highlighting significant interactions between estrogen and progesterone that explain midluteal increases in emotional eating. Future work should explore mechanisms (e.g., gene-hormone interactions) that contribute to both within-and between-subjects differences in emotional eating.