Prognostic Factors in Stage III Non-Small-Cell Lung Cancer Patients
Prognostic Factors in Stage III Non-Small-Cell Lung Cancer Patients
复制标题
III 期非小细胞肺癌患者的预后因素
DOI:
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发表时间:
2016
影响因子:
--
通讯作者:
N. Turan
中科院分区:
文献类型:
--
作者:
S. Urvay;B. Yucel;E. Erdiş;N. Turan
Aim: The objective of this study is to investigate prognostic factors affecting survival of patients undergoing concurrent or sequential chemoradiotherapy (CRT) for stage III non-small-cell lung cancer (NSCL). Methods and materials: We retrospectively reviewed the clinical records of 148 patients with advanced, inoperable stage III NSCLC, who were treated between 2007 and 2015. Results: The median survival was found to be 19 months and 3-year overall survival was 27%. Age (<65 vs ≥65 years, p=0.026), stage (IIIA vs IIIB, p=0.033), dose of radiotherapy (RT) (<60 vs ≥60 Gy, p=0.024) and treatment method (sequential chemotherapy+RT vs concurrent CRT, p=0.023) were found to be factors affecting survival in univariate analyses. Gender, histological subtype, weight loss during CRT, performance status, induction/consolidation chemotherapy and presence of comorbidities did not affect survival (p>0.050). Conclusion: Young age, stage IIIA, radiotherapy dose and concurrent chemoradiotherapy may positively affect survival in stage III NSCL cases.
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影响因子:
45.3
作者:
Vokes, Everett E.;Herndon, James E., II;Green, Mark R.
通讯作者:
Green, Mark R.
影响因子:
45.3
作者:
FINKELSTEIN, DM;ETTINGER, DS;RUCKDESCHEL, JC
通讯作者:
RUCKDESCHEL, JC
DOI:
10.1093/jnci/djr325
发表时间:
2011-10-01
期刊:
JOURNAL OF THE NATIONAL CANCER INSTITUTE
影响因子:
--
作者:
Curran, Walter J., Jr.;Paulus, Rebecca;Cox, James D.
通讯作者:
Cox, James D.
影响因子:
120.7
作者:
Piccirillo, JF;Tierney, RM;Spitznagel, EL
通讯作者:
Spitznagel, EL