Liver fluke infections in cattle and sheep

Liver fluke infections in cattle and sheep
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牛和羊的肝吸虫感染

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发表时间:
2017
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通讯作者:
A. Forbes
A. Forbes
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作者:
A. Forbes

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吸虫,肝片形吸虫,是一个世界性的温带地区,可以感染各种各样的野生和家养哺乳动物物种,包括man.Host反应不同的物种之间的对比,本文重点介绍牛和羊,这两个类的牲畜中,肝片形吸虫病承担最大的经济重要性。在绵羊中,急性肝片形吸虫病是一种严重的、可能致命的疾病,它是由迁移性幼年吸虫引起的肝实质损伤和出血引起的。相比之下,实质阶段对牛的影响有限,急性形式的疾病极为罕见。虽然没有证据表明对肝片吸虫的功能性获得性免疫应答,但牛提供了一个不太友好的环境,可能是由于寄生的胆管发生了深刻的变化,使其成为不适合饲养吸虫的栖息地。因此,在未经治疗的牛中,许多肝吸虫在感染后18个月内死亡,而不是在感染后18个月内死亡。
The trematode, Fasciola hepatica, is a cosmopolitan parasite of temperate regions that can infect a wide variety of wild and domestic mammalian species, including man. Host-responses differ amongst different species and this article focuses on the contrast between cattle and sheep, the two classes of livestock in which fasciolosis assumes the greatest economic importance. In the sheep, acute fasciolosis resulting from parenchymal damage to the liver and haemorrhage caused by migrating juvenile flukes is a severe and potentially fatal disease. In contrast, the parenchymal stages have limited effects in cattle and the acute form of the disease is extremely rare. Though there is no evidence for a functional, acquired immune response to Fasciola hepatica, cattle provide a less hospitable environment, probably due to the profound changes in parasitised bile ducts, which render them as unsuitable habitats for feeding fluke. Consequently, in untreated cattle, many liver fluke die within 18 months of infection, t...