Accounting for Nulliparity in the Prediction of Hypoxic-Ischemic Encephalopathy Using Cardiotocography.
Accounting for Nulliparity in the Prediction of Hypoxic-Ischemic Encephalopathy Using Cardiotocography.
复制标题
DOI：
10.1109/bhi58575.2023.10313456
复制
发表时间：
2023-10
期刊：
影响因子：
--
通讯作者：
Kearney, Robert E.
中科院分区：
文献类型：
--
作者：
Vargas-Calixto, Johann;Wu, Yvonne W.;Kuzniewicz, Michael;Cornet, Marie-Coralie;Forquer, Heather;Gerstley, Lawrence;Hamilton, Emily;Warrick, Philip A.;Kearney, Robert E.
未产妊娠，即母亲以前没有生产过的妊娠，与产程较长有关，因此使胎儿暴露于更多的宫缩和其他不利的产时状况，如绒毛膜羊膜炎。本研究的目的是测试是否考虑到无产可以提高胎儿患缺氧缺血性脑病（HIE）风险增加的检测。在分娩过程中，临床医生评估胎儿心率和子宫压力信号，以确定胎儿有发展为HIE的风险。在这项研究中，我们对40,831例新生儿的胎儿心率和子宫压力特征进行了随机森林分类，其中包括374例HIE。我们分析了一种双路径分类方法，分别分析了无产和多产母亲的胎儿，以及一种单路径分类方法，将无产的临床变量作为分类特征。我们将这两种方法与没有关于母亲平价信息的单路径分类器进行了比较。我们还将我们的结果与每组的剖腹产率进行了比较，剖腹产在临床上用于阻断HIE的进展。所有的分类器检测到更多的胎儿发生HIE比观察到的剖腹产率，但考虑到无产并没有提高性能。
Nulliparous pregnancies, those where the mother has not previously given birth, are associated with longer labors and hence expose the fetus to more contractions and other adverse intrapartum conditions such as chorioamnionitis. The objective of the present study was to test if accounting for nulliparity could improve the detection of fetuses at increased risk of developing hypoxic-ischemic encephalopathy (HIE). During labor, clinicians assess the fetal heart rate and uterine pressure signals to identify fetuses at risk of developing HIE. In this study, we performed random forest classification using fetal heart rate and uterine pressure features from 40,831 births, including 374 that developed HIE. We analyzed a two-path classification approach that analyzed separately the fetuses from nulliparous and multiparous mothers, and a one-path classification approach that included the clinical variable for nulliparity as a classification feature. We compared these two approaches to a one-path classifier that had no information about the parity of the mothers. We also compared our results to the rate of Caesarean deliveries in each group, which is used clinically to interrupt the progression towards HIE. All the classifiers detected more fetuses that developed HIE than the observed Caesarean rate, but accounting for nulliparity did not improve performance.
影响因子：
3.1
作者：
Locatelli, Anna;Lambicchi, Laura;Paterlini, Giuseppe
通讯作者：
Paterlini, Giuseppe
影响因子：
3.6
作者：
Lee, Anne C. C.;Kozuki, Naoko;Blencowe, Hannah;Vos, Theo;Bahalim, Adil;Darmstadt, Gary L.;Niermeyer, Susan;Ellis, Matthew;Robertson, Nicola J.;Cousens, Simon;Lawn, Joy E.
通讯作者：
Lawn, Joy E.
影响因子：
13.8
作者：
Farquhar, Cynthia M.;Armstrong, Sarah;Sadler, Lynn
通讯作者：
Sadler, Lynn