Cardiac troponin levels following monitored epileptic seizures
Cardiac troponin levels following monitored epileptic seizures
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DOI：
10.1212/01.wnl.0000065881.46964.4f
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发表时间：
2003-05-27
期刊：
影响因子：
9.9
通讯作者：
Jaffe, AS
中科院分区：
文献类型：
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作者：
Woodruff, BK;Britton, JW;Jaffe, AS
与心肌损伤相关的心律失常是癫痫患者不明原因猝死的可能机制。作者在监测癫痫发作后测量了11例患者的连续心肌肌钙蛋白水平。使用高度敏感的检测和标准，没有肌钙蛋白升高，表明心肌损伤不会发生在简单的癫痫发作。发作后肌钙蛋白升高提示继发于神经心源性机制或原发性心脏因素的心脏损伤，提示进一步评估。
Cardiac arrhythmia associated with myocardial injury is a proposed mechanism for sudden unexplained death in epilepsy. The authors measured serial cardiac troponin levels in 11 patients after monitored seizures. Using highly sensitive assays and criteria, no troponin elevations were seen, indicating that myocardial injury does not occur during uncomplicated seizures. An elevation in postictal troponin elevations should suggest the presence of cardiac injury secondary to neurocardiogenic mechanisms or primary cardiac factors, prompting further evaluation.