Incidence of Myopia in High School Students with and without Red-Green Color Vision Deficiency
Incidence of Myopia in High School Students with and without Red-Green Color Vision Deficiency
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红绿色视觉缺陷高中生近视发生率
DOI：
10.1167/iovs.07-1362
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发表时间：
2009-04-01
影响因子：
4.4
通讯作者：
Pao, Kristina E. Yi-Hwa
中科院分区：
文献类型：
--
作者：
Qian, Yi-Shan;Chu, Ren-Yuan;Pao, Kristina E. Yi-Hwa
目的：通过检测患有和不患有色觉缺陷（CVD）的高中生的屈光不正和眼轴长度，研究色觉对近视发展的影响。
方法：进行了一项基于学校的横断面整群抽样研究，对16539名高中生的色觉和屈光不正进行了检测。使用假同色图对学生进行CVD筛查。对未通过该测试的学生使用 Farnsworth - Munsell 100 - 色相测试来确认CVD，该测试还用于对亚型（红色盲或绿色盲）进行分类。为每个CVD受试者选择三名在五个近视风险因素上匹配的同学，组成正常色觉（CN）对照组。进行眼科检查以确定屈光状态和眼轴长度。
结果：在这些学生中，发现309人患有红绿色觉CVD，927人被选作CN对照组。CVD组的近视患病率（45.6%）显著低于CN组（65.8%；P < 0.001）。CVD组在屈光方面也比CN组近视程度更低（P < 0.001），并且红色盲受试者的眼轴长度比对照组短（P = 0.007）。
结论：色觉缺陷似乎影响近视的发展。在CVD患者中观察到的较低近视发生率可能与L/M色觉机制功能降低有关。（《眼科研究与视觉科学》2009年；50卷：1598 - 1605页）DOI:10.1167/iovs.07 - 1362
PURPOSE. To investigate the influence of color vision on myopia development by testing refraction error and axial length of the eye for high school students with and without color vision deficiency (CVD).METHODS. A school-based cross-sectional, cluster sample study was conducted to test the color vision and refractive error of 16,539 high school students. Students were screened for CVD using a pseudoisochromatic plate. CVD was confirmed in students failing the test using a Farnsworth- Munsell 100-Hue Test which also served to classify the subtype (protan or deutan). Three classmates of each CVD subject, matched in five myopia risk factors, were chosen to form the normal color vision (CN) control group. Ophthalmic examinations were performed to determine refractive status and axial length.RESULTS. Of the students, 309 were found to have red-green CVD and 927 were selected as the CN control group. The prevalence of myopia in the CVD group (45.6%) was significantly lower than that of the CN group (65.8%; P < 0.001). The CVD group was also less myopic in refraction (P < 0.001) than CN, and protan subjects had shorter axial lengths than those in the control group (P = 0.007).CONCLUSIONS. Color vision deficiencies appear to influence the development of myopia. The observed lower incidence of myopia in people with CVD may be linked to the reduced functionality of the L/M chromatic mechanism. (Invest Ophthalmol Vis Sci. 2009; 50: 1598-1605) DOI:10.1167/iovs.07-1362