Quality of life in patients with postural tachycardia syndrome

Quality of life in patients with postural tachycardia syndrome
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DOI:
10.4065/77.6.531
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发表时间:
2002-06-01
影响因子:
8.9
通讯作者:
Low, PA
Low, PA
中科院分区:
医学2区
文献类型:
--
作者:
Benrud-Larson, LM;Dewar, MS;Low, PA

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目的:为了量化生活质量,并确定人口统计学和临床相关的功能在一个良好的特征样本的患者体位性心动过速syndrome(POTS).Patients和方法:前瞻性的患者是那些在马约诊所自主神经疾病实验室从2000年9月至2001年6月。神经科医生根据既定标准对POTS进行诊断。患者完成了一个问卷包,其中包括生活质量的措施(36项。简明健康调查表[SF-36])和症状严重程度(自主神经症状特征)。额外的临床信息是从病历中提取的。结果:94例患者(89%为女性,平均年龄34.2岁)参加了这项研究。POTS患者报告了SF-36多个领域的损害。与健康人群相比,身体功能、角色功能、身体疼痛、一般健康状况、活力和社会功能均显著受损(P
Objectives: To quantify quality of life and identify demographic and clinical correlates of functioning in a well-characterized sample of patients with postural tachycardia syndrome (POTS).Patients and Methods: Prospective patients were those seen at the Mayo Clinic Autonomic Disorders Laboratory from September 2000 to June 2001. Neurologists made diagnoses of POTS according to established criteria. Patients completed a questionnaire packet that included measures of quality of life (36-Item. Short-Form Health Survey [SF-36]) and symptom severity (Autonomic Symptom Profile). Additional clinical information was abstracted from medical records.Results: Ninety-four patients (89% female; mean age, 34.2 years) were enrolled in the study. Patients with POTS reported impairment across multiple domains on the SF-36. Physical functioning, role functioning, bodily pain, general health, vitality, and social functioning were all significantly impaired compared with a healthy population (P