Estimation of skeletal muscle mass by bioelectrical impedance analysis
Estimation of skeletal muscle mass by bioelectrical impedance analysis
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DOI：
10.1152/jappl.2000.89.2.465
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发表时间：
2000-08-01
影响因子：
3.3
通讯作者：
Ross, R
中科院分区：
文献类型：
--
作者：
Janssen, I;Heymsfield, SB;Ross, R
本研究的目的是建立并交叉验证使用生物电阻抗分析（BLA）估计骨骼肌（SM）质量的预测方程。在两个不同的实验室中，对388名年龄在18-86岁的男性和女性的多种族样本进行了磁共振成像测定的全身SM质量与BIA测量结果进行了比较。在每个实验室中，利用高加索受试者的数据推导了从BIA测量中预测SM质量的方程。然后将这些方程应用于来自其他实验室的高加索受试者，以交叉验证BIA方法。由于方程交叉验证（即没有不同），两个实验室的数据被合并以生成最终的回归方程[图形]，其中Ht为身高，单位为厘米；R为BIA电阻，单位为欧姆；对于性别，男性= 1，女性= 0；年龄是以年为单位的。回归方程估计的r(2)和SE分别为0.86和2.7 kg（9%）。白种人推导的公式适用于西班牙裔和非洲裔美国人，但低估了亚洲人的SM质量。这些结果表明，BIA方程提供了年龄和肥胖程度不同的健康成年人SM质量的有效估计。
The purpose of this study was to develop and cross-validate predictive equations for estimating skeletal muscle (SM) mass using bioelectrical impedance analysis (BLA). Whole body SM mass, determined by magnetic resonance imaging, was compared with BIA measurements in a multiethnic sample of 388 men and women, aged 18-86 yr, at two different laboratories. Within each laboratory, equations for predicting SM mass from BIA measurements were derived using the data of the Caucasian subjects. These equations were then applied to the Caucasian subjects from the other laboratory to cross-validate the BIA method. Because the equations cross-validated (i.e., were not different), the data from both laboratories were pooled to generate the final regression equation[GRAPHICS]where Ht is height in centimeters; R is BIA resistance in ohms; for gender, men = 1 and women = 0; and age is in years. The r(2) and SE of estimate of the regression equation were 0.86 and 2.7 kg (9%), respectively. The Caucasian derived equation was applicable to Hispanics and African-Americans, but it underestimated SM mass in Asians. These results suggest that the BIA equation provides valid estimates of SM mass in healthy adults varying in age and adiposity.