Neural correlates of mental rehearsal in dorsal premotor cortex
Neural correlates of mental rehearsal in dorsal premotor cortex
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DOI：
10.1038/nature03005
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发表时间：
2004-10-21
期刊：
影响因子：
64.8
通讯作者：
Kalaska, JF
中科院分区：
文献类型：
--
作者：
Cisek, P;Kalaska, JF
行为和成像研究表明，当人类在心理上排练一个熟悉的动作时，他们会执行一些与公开运动表现相同的神经操作（1-9）。类似地，在观察动作的过程中，神经激活出现在许多通常用于表演的相同大脑区域，包括运动前皮质（6-9）。在这里，我们提出的行为证据表明，猴子在观察与一个很好的学习运动任务相关的感觉事件时，也参与了心理排练。此外，大多数任务相关的神经元在背侧前运动皮层表现出相同的活动模式，在观察期间的性能，甚至在一个短暂的延迟期之前，任何实际观察到的运动。这种活动可能是一个单神经元相关的内隐心理排练。
Behavioural and imaging studies suggest that when humans mentally rehearse a familiar action they execute some of the same neural operations used during overt motor performance(1-9). Similarly, neural activation is present during action observation in many of the same brain regions normally used for performance, including premotor cortex(6-9). Here we present behavioural evidence that monkeys also engage in mental rehearsal during the observation of sensory events associated with a well-learned motor task. Furthermore, most task-related neurons in dorsal premotor cortex exhibit the same activity patterns during observation as during performance, even during an instructed-delay period before any actual observed motion. This activity might be a single-neuron correlate of covert mental rehearsal.