POSITRON-EMISSION TRANSAXIAL TOMOGRAPH FOR NUCLEAR IMAGING (PETT)

POSITRON-EMISSION TRANSAXIAL TOMOGRAPH FOR NUCLEAR IMAGING (PETT)
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DOI:
10.1148/114.1.89
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发表时间:
1975-01-01
期刊:
影响因子:
19.7
通讯作者:
MULLANI, NA
MULLANI, NA
中科院分区:
医学1区
文献类型:
--
作者:
TERPOGOSSIAN, MM;PHELPS, ME;MULLANI, NA

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研制了一种用于获得含有正电子发射放射性药物的器官切片的发射轴向图像的装置。探测系统是一个由24个NaI(Tl)探测器组成的六边形阵列,连接到符合电路,以实现湮没光子的“电子”准直。图像由计算机应用算法形成,该算法提供活性分布的定量重建。计算机模拟,幻影和动物研究表明,这种方法是能够提供更好的对比度和分辨率比闪烁相机获得的图像。讨论了正电子与单光子重建断层成像的优点。
An apparatus was developed for obtaining emission transaxial images of sections of organs containing positron-emitting radiopharmaceuticals. The detection system is a hexagonal array of 24 NaI (Tl) detectors connected to coincidence circuits to achieve the “electronic” collimation of annihilation photons. The image is formed by a computer-applied algorithm which provides quantitative reconstruction of the distribution of activity. Computer simulations, phantom and animal studies show that this approach is capable of providing images of better contrast and resolution than are obtained with scintillation cameras. Advantages of positronvs.single photon reconstruction tomography are discussed.