Chemical composition and evaluation of acetylcholinesterase inhibition and antioxidant activity of essential oil from Dalmatian endemic species Pinus nigra Arnold ssp. dalmatica (Vis.) Franco
Chemical composition and evaluation of acetylcholinesterase inhibition and antioxidant activity of essential oil from Dalmatian endemic species Pinus nigra Arnold ssp. dalmatica (Vis.) Franco
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达尔马提亚特有种黑松精油的化学成分、乙酰胆碱酯酶抑制和抗氧化活性评价。
DOI：
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发表时间：
2011
期刊：
影响因子：
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通讯作者：
M. Miloš
中科院分区：
文献类型：
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作者：
O. Politeo;I. Botica;T. Bilušić;M. Jukić;Ivana Carev;F. Burčul;M. Miloš
本文对我国特有种黑松Pinus nigra Arnold ssp.挥发油的化学成分和生物活性（乙酰胆碱酯酶抑制活性和抗氧化活性）进行了研究。dalmatica（维斯）佛朗哥被调查了。经GC-FID和GC-MS鉴定，α-蒎烯、β-蒎烯、大根香叶烯D和β-香芹烯为主要成分。黑腐病菌达尔马提亚挥发油对乙酰胆碱酯酶（AChE）具有较强的抑制活性，这可能与其主要单萜成分（S-α-蒎烯）及其混合物（S-α-蒎烯：S-β-蒎烯和R-α-蒎烯：S-β-蒎烯，比例为3：2）具有较强的AChE抑制活性有关。黑胡椒挥发油P. nigra ssp.通过DPPH自由基清除法、铁还原抗氧化能力（FRAP）和硫代巴比妥酸活性物质（TBARS）测定法对dalmatica的抗氧化活性进行了研究。
In the present study, the chemical composition and biological activity (acetylcholinesterase inhibition and antioxidant activity) of essential oil from endemic species Pinus nigra Arnold ssp. dalmatica (Vis.) Franco was investigated. α-Pinene, β-pinene, germacrene D and β-caryophyllene were identified by GC-FID and GC-MS as dominant components of the oil. P. nigra ssp. dalmatica essential oil showed relatively high inhibitory activity on acetylcholinesterase (AChE), which can be in relation with good AChE inhibitory activity of pure main monoterpene components of the oil (S-α-pinene) and their mixtures (S-α-pinene:S-β-pinene and R-α-pinene:S-β-pinene, in ratio 3:2). Essential oil from P. nigra ssp. dalmatica did not show significant antioxidant activity tested by three methods: DPPH radical scavenging method, Ferric Reducing Antioxidant Potential (FRAP) and Thiobarbituric Acid Reactive Species (TBARS) assays.
DOI：
10.1046/j.1525-1373.1999.d01-140.x
发表时间：
1999-12-01
影响因子：
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作者：
Floyd, RA
通讯作者：
Floyd, RA