Gender and the use of antiretroviral treatment in resource-constrained settings: Findings from a multicenter collaboration
Gender and the use of antiretroviral treatment in resource-constrained settings: Findings from a multicenter collaboration
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DOI：
10.1089/jwh.2007.0353
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发表时间：
2008-01-01
影响因子：
3.5
通讯作者：
Low, Nicola
中科院分区：
文献类型：
--
作者：
Braitstein, Paula;Boulle, Andrew;Low, Nicola
目的：为了比较艾滋病毒感染的成年人接受高活性抗逆转录病毒治疗（HAART）在资源有限的设置与艾滋病毒感染的性别分布的估计的性别分布;描述女性和男性接受HAART.Methods的临床特征：在低收入国家的抗逆转录病毒治疗，ART-LINC协作是一个网络的诊所提供HAART在非洲，拉丁美洲和亚洲。我们比较了艾滋病规划署的艾滋病毒感染的性别分布的数据与接受HAART的女性和男性的比例在ART-LINC Collaboration.Results：在13个国家的29个中心参加。在33 164人中，有19 989人（60.3%）是妇女。在ART-LINC中心接受HAART治疗的妇女比例与联合国艾滋病规划署估计的艾滋病毒感染妇女比例相似或更高，只有两个中心除外。在乌干达的一个中心和印度的一个中心，接受高效抗逆转录病毒疗法的妇女人数少于联合国艾滋病规划署的数据。考虑到异质性跨队列，女性比男性年轻，不太可能有先进的艾滋病毒感染，更有可能是贫血在HAART initiation.Conclusions：妇女在资源有限的设置不一定是不利的，在他们获得HAART。需要更加注意确保感染艾滋病毒的男子寻求护理并开始高效抗逆转录病毒疗法。
Aims: To compare the gender distribution of HIV-infected adults receiving highly active antiretroviral treatment (HAART) in resource-constrained settings with estimates of the gender distribution of HIV infection; to describe the clinical characteristics of women and men receiving HAART.Methods: The Antiretroviral Therapy in Lower-Income Countries, ART-LINC Collaboration is a network of clinics providing HAART in Africa, Latin America, and Asia. We compared UNAIDS data on the gender distribution of HIV infection with the proportions of women and men receiving HAART in the ART-LINC Collaboration.Results: Twenty-nine centers in 13 countries participated. Among 33,164 individuals, 19,989 (60.3%) were women. Proportions of women receiving HAART in ART-LINC centers were similar to, or higher than, UNAIDS estimates of the proportions of HIV-infected women in all but two centers. There were fewer women receiving HAART than expected from UNAIDS data in one center in Uganda and one center in India. Taking into account heterogeneity across cohorts, women were younger than men, less likely to have advanced HIV infection, and more likely to be anemic at HAART initiation.Conclusions: Women in resource-constrained settings are not necessarily disadvantaged in their access to HAART. More attention needs to be paid to ensuring that HIV-infected men are seeking care and starting HAART.