Nucleophilic deoxyfluorination of catechols.
Nucleophilic deoxyfluorination of catechols.
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DOI：
10.1021/ol200808q
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发表时间：
2011-04
期刊：
影响因子：
5.2
通讯作者：
Hiroyuki Nemoto;T. Nishiyama;S. Akai
中科院分区：
文献类型：
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作者：
Hiroyuki Nemoto;T. Nishiyama;S. Akai
邻苯二酚的两个羟基之一的亲核脱氧氟代已通过Umpolung概念开发。这种方法被成功地应用于天然存在的儿茶酚，如儿茶素和多巴胺，以产生新的氟化类似物。
Nucleophilic deoxyfluorinaiton of one of the two hydroxyl groups of catechols has been developed via the Umpolung concept. This method was successively applied to naturally occurring catechols, such as catechins and dopamine, to produce novel fluorinated analogues.