Retinal artery pressure and cerebral artery perfusion pressure in cerebrovascular occlusive disease.
Retinal artery pressure and cerebral artery perfusion pressure in cerebrovascular occlusive disease.
复制标题
脑血管闭塞性疾病中的视网膜动脉压和脑动脉灌注压。
作者：
J. Little;R. Tomsak;Z. Ebrahim;A. Furlan
本研究的目的是测量颞浅动脉到大脑中动脉（STA-MCA）搭桥术患者的视网膜动脉压（RAP）和皮质动脉压（CAP），研究两者之间的关系，并评价我们在RAP基础上预测CAP的能力。44例行搭桥手术的患者包括同侧颈内动脉（ICA）闭塞26例（I组），双侧颈内动脉闭塞5例（II组），眼动脉近端ICA狭窄4例（III组），OA远端ICA狭窄2例（IV组），OA远端ICA闭塞3例（V组），MCA狭窄2例（VI组），MCA闭塞2例（VII组）。5例因无症状囊性动脉瘤接受开颅手术的患者作为对照。平均RAP （MRAP）通过眼动测定仪（ODM）测量，并以平均全身动脉血压（即MRAP/MSAP）的比值表示。OA近端ICA闭塞组I、II和III组的平均MRAP/MSAP显著低于对照组（P = 0.0001）和OA远端闭塞病变组IV、V、VI和VII组（P = 0.0001）。I组和II组6例静脉淤滞性视网膜病变患者的平均MRAP/MSAP为0.18 +/- 0.11。平均皮质动脉压（MCAP）通过将26号针头插入小皮质动脉测量，并以MCAP/MSAP比值表示。除第三组外，其余各组平均MCAP/MSAP均小于0.50。（摘要删节250字）
The objectives of the investigation were to measure the retinal artery pressure (RAP) and cortical artery pressure (CAP) in patients undergoing superficial temporal artery to middle cerebral artery (STA-MCA) bypass, to study the relationship between these pressures, and to evaluate our ability to predict CAP on the basis of RAP. The 44 patients undergoing bypass surgery included 26 with ipsilateral internal carotid artery (ICA) occlusion (Group I), 5 with bilateral ICA occlusion (Group II), 4 with inaccessible ICA stenosis proximal to the ophthalmic artery (OA) (Group III), 2 with ICA stenosis distal to the OA (Group IV), 3 with ICA occlusion distal to the OA (Group V), 2 with MCA stenosis (Group VI), and 2 with MCA occlusion (Group VII). Five patients undergoing craniotomy for an asymptomatic saccular aneurysm were used as controls. Mean RAP (MRAP) was measured by ophthalmodynamometry (ODM) and was expressed as a ratio of the mean systemic arterial blood pressure (i.e., MRAP/MSAP). The mean MRAP/MSAP for combined Groups I, II, and III with ICA occlusion proximal to the OA was significantly lower than both the control group (P = 0.0001) and the combined Groups IV, V, VI, and VII with occlusive lesions distal to the OA (P = 0.0001). Six patients in Groups I and II with venous stasis retinopathy had a mean MRAP/MSAP of 0.18 +/- 0.11. Mean cortical artery pressure (MCAP) was measured by inserting a 26 gauge needle into a small cortical artery and was expressed as the MCAP/MSAP ratio. Mean MCAP/MSAP was less than 0.50 for all groups except Group III.(ABSTRACT TRUNCATED AT 250 WORDS)