Morphometry of nuclear rings at high electron microscopic resolution.
Morphometry of nuclear rings at high electron microscopic resolution.
复制标题
高电子显微镜分辨率下核环的形态测量。
DOI：
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复制
发表时间：
1987
期刊：
影响因子：
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通讯作者：
G. Bahr
中科院分区：
文献类型：
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作者：
J. Aréchaga;J. Diaz;G. Bahr
In studying the fine structure of the nuclear chromatin, a new organelle was discovered, the nuclear ring. In its isolated form, this structure is rather like a geometric torus: a smooth, structureless ring. This paper presents the results of electron microscopic morphologic measurements on 424 isolated rings, i.e., rings found free of any fibrous connections. From the measurements of inner and outer diameters, other geometric features were also calculated. Overall, the size of the rings varied about fivefold. Inner and outer diameters were closely correlated, suggesting a rather stable thickness of the ring itself. The significance of the nuclear ring is as yet poorly understood. With its occasionally intimate connections to both chromatin fibers and to the inside of the inner nuclear envelope, its role is likely to be a crucial one. The membrane covering its opening is none other than the bilayer of the nuclear envelope. The concept of a patent opening or "pore" does not appear tenable in the face of this and related findings.
