The principles and feasibility of disease eradication
The principles and feasibility of disease eradication
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DOI：
10.1016/j.vaccine.2011.04.006
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发表时间：
2011-12-30
期刊：
影响因子：
5.5
通讯作者：
Cochi, Stephen L.
中科院分区：
文献类型：
--
作者：
Dowdle, Walter R.;Cochi, Stephen L.
根除天花将根除疾病视为全球卫生公平方面的一项里程碑式的公共卫生成就。根除疾病的原则概括为四个条件：生物学可行性、充足的公共卫生基础设施、充足的资金和持续的政治/社会意愿。在存在这种现象的地方，如果没有全球倡议，就会在全国范围内进行根除。评估全球根除的可行性需要确定所有地区国家的星座差距，并确定填补差距的人力和财力资源。根除病毒所带来的经济和人道主义效益具有很强的吸引力。全球脊髓灰质炎和麦地那龙线虫病防治工作正在进行中。美洲已实现区域性消灭麻疹和风疹，并已提议消灭其他疾病。关于消除疾病的全球决策应包括仔细考虑机会成本和有限的全球卫生资源的优先顺序，以提供最适当、成本效益和公平的疾病控制结果。 (C) 2011 Elsevier Ltd. 保留所有权利。
Smallpox eradication framed disease eradication as a monumental public health achievement in global health equity. The principles of disease eradication are encapsulated in a constellation of four conditions: biologic feasibility, adequate public health infrastructure, sufficient funding, and sustained political/societal will. Where the constellation exists, national eradication occurs in the absence of a global initiative. Assessing the feasibility of global eradication requires determining the constellation gaps for nations of all regions and identifying the human and financial resources to fill the gaps. The economic and humanitarian benefits of eradication have strong appeal. Global polio and guinea worm efforts are underway. Regional eradication of measles and rubella has been achieved in the Americas and other diseases have been proposed. Global decisions on disease eradication should include careful consideration of opportunity costs and prioritization of limited global health resources, with the objective of providing the most appropriate, cost-beneficial, and equitable outcome of disease control. (C) 2011 Elsevier Ltd. All rights reserved.