Community attitudes towards emergency research and exception from informed consent
Community attitudes towards emergency research and exception from informed consent
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DOI：
10.1016/j.resuscitation.2009.08.019
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发表时间：
2009-12-01
期刊：
影响因子：
6.5
通讯作者：
Miller, Kathleen
中科院分区：
文献类型：
--
作者：
Biros, Michelle H.;Sargent, Corey;Miller, Kathleen
目的：为了确定公众对紧急研究的态度，知情同意（EFIC）的例外和一个具体的建议使用EFIC.Methods的临床试验：作为计划中的社区咨询活动的一部分，在一个受欢迎的公共场所进行了调查。参与者回答了人口统计学问题，然后被问及他们对紧急研究中具体描述的同意情况的意见，包括拟议的EFIC试验。多元逻辑和线性回归被用来确定与特定的attitude.Results：1901调查完成的受访者的特点。大多数受访者支持紧急研究（88%）和由合法授权代表代理同意的概念（78%）。至于“外汇基金收入”的概念，则较少人支持（35%），但“外汇基金收入”的应用则较受欢迎，特别是应用于被访者本身（51%）。社区认为拟议的EFIC研究是可以接受的（82%）;少数人有担忧，但大多数与患者安全有关，而不是EFIC。受教育程度低，收入低的受访者不太可能表达意见的同意和研究concepts described.Conclusions：紧急研究和建议EFIC试验支持在这个社区。EFIC的概念不太受支持，但当描述特定试验或受访者自己考虑EFIC时，它更容易被接受。具体的受访者的特点与研究的态度，这可以帮助发展有意义的社区咨询活动。(C)2009爱思唯尔爱尔兰有限公司保留所有权利。
Objective: To determine public attitudes towards emergency research, exception from informed consent (EFIC) and a specific proposed clinical trial using EFIC.Methods: As part of a planned community consultation activity, a survey was conducted at a popular public venue. Participants answered demographic questions and then were asked their opinions on specifically described consent circumstances in emergency research, including the proposed EFIC trial. Multiple logistic and linear regression were used to determine respondent characteristics associated with specific attitudes.Results: 1901 Surveys were completed. The majority of respondents supported emergency research (88%) and the concept of surrogate consent by a legally authorized representative (78%). The concept of EFIC was less well supported (35%) but the application of EFIC was more accepted, especially when EFIC was applied to the respondent themselves (51%). The Community believed the proposed EFIC study was acceptable (82%); a minority had concerns but most were related to patient safety and not to EFIC. Respondents with less education and lower incomes were less likely to express opinions about the consent and research concepts described.Conclusions: Emergency research and the proposed EFIC trial is supported in this community. The concept of EFIC is less well supported but is more acceptable when a specific trial is described or when respondents consider EFIC for themselves. Specific respondent characteristics are associated with attitudes about research; this can assist in development of meaningful community consultation activities. (C) 2009 Elsevier Ireland Ltd. All rights reserved.