Non-invasive tests for the diagnosis of helicobacter pylori: state of the art.
Non-invasive tests for the diagnosis of helicobacter pylori: state of the art.
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DOI：
10.23750/abm.v89i8-s.7910
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发表时间：
2018-12-17
期刊：
影响因子：
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通讯作者：
De' Angelis, Gian Luigi
中科院分区：
文献类型：
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作者：
Kayali, Stefano;Aloe, Rosalia;De' Angelis, Gian Luigi
通常，非侵入性测试是诊断幽门螺杆菌（HP）感染的第一种方法。其中，血清学试验、粪便抗原研究和尿素呼气试验应用最多。不建议在低流行率人群中使用抗HP抗体，而且它们不能显示正在进行的感染，但它们只能证明与细菌接触。此外，它们可以在根除感染后持续很长一段时间，因此，它们不应用于验证根除治疗的成功。粪便抗原研究和尿素呼气试验（UBT）在诊断和根除治疗后的随访中都是有用的。粪便抗原试验比尿素呼气试验便宜，敏感性和特异性相似。非侵入性测试无法诊断HP感染的相关并发症。
Usually, non-invasive tests are the first methods for diagnosing Helicobacter pylori (HP) infection. Among these, serological test, stool antigen research and urea breath test are the most used. Antibodies anti-HP are not recommended in low prevalence population, moreover they cannot reveal an ongoing infection, but they only prove a contact with the bacterium. Also, they can persist for a long time after the eradication of the infection, therefore, they should not be used to verify the success of eradication therapy. Stool antigen research and Urea Breath Test (UBT) are useful both in diagnosis and during follow-up after eradication treatment. The stool antigen test is cheaper than Urea breath test with similar sensitivity and specificity. Non-invasive tests are not able to diagnose the associated complications to HP infection.