Survey of the number of two-component response regulator genes in the complete and annotated genome sequences of prokaryotes
Survey of the number of two-component response regulator genes in the complete and annotated genome sequences of prokaryotes
复制标题
DOI：
10.1016/s0378-1097(04)00004-7
复制
发表时间：
2004-02-16
影响因子：
2.1
通讯作者：
Ashby, MK
中科院分区：
文献类型：
--
作者：
Ashby, MK
潜在应答调节基因的数量是根据古菌和细菌完整的且有注释的基因组序列确定的。每个生物体中各类应答调节因子的数量都已列出，这些数量主要是通过BLASTP搜索确定的，但如果有基因类别列表可供参考，也会加以参照。这项调查表明，对于细菌而言，潜在应答调节基因的总数与基因组复杂性（潜在蛋白质编码基因的数量）以及生物体的生活方式/栖息地之间存在联系。生活方式和基因组复杂性越高，每个基因组中潜在应答调节基因的平均数量就越多，这表明更高程度的复杂性需要对基因表达和细胞活动进行更高级别的控制。这项研究的详细结果可在以下网址在线获取：http://www.mona.uwi.edu/biochem/courses/bc31m/table2.xls以及http://www.mona.uwi.edu/biochem/courses/bc31m/table2genelist.pdf。（C）2004年欧洲微生物学会联合会。由爱思唯尔出版社出版。保留所有权利。
The numbers of potential response regulator genes were determined from the complete and annotated genome sequences of Archaea and Bacteria. The numbers of each class of response regulators are shown for each organism, determined principally from BLASTP searches, but with reference to the gene category lists where available. The survey shows that for Bacteria there is a link between the total number of potential response regulator genes and both the genome complexity (number of potential protein-coding genes) and the organism's lifestyle/habitat. Increasingly complex lifestyles and genome complexities are matched by an increase in the average number of potential response regulator genes per genome, indicating that a higher degree of complexity requires a higher level of control of gene expression and cellular activity. Detailed results of this study are available online at http://www.mona.uwi.edu/biochem/courses/bc31m/ table2.xls and http://www.mona.uwi.edu/biochem/courses/bc31m/table2genelist.pdf. (C) 2004 Federation of European Microbiological Societies. Published by Elsevier B.V. All rights reserved.