Characterization of urinary concentrations of heavy metals among socioeconomically disadvantaged black pregnant women
Characterization of urinary concentrations of heavy metals among socioeconomically disadvantaged black pregnant women
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DOI：
10.1007/s10661-020-8163-z
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发表时间：
2020-02-27
影响因子：
3
通讯作者：
Symanski, Elaine
中科院分区：
文献类型：
--
作者：
Han, Inkyu;Whitworth, Kristina W.;Symanski, Elaine
本研究的目的是利用从社会经济地位较低的黑人孕妇身上收集的生物样本来描述金属暴露的特征。我们收集了 2017 年 3 月 27 日至 2017 年 4 月 11 日访问德克萨斯州休斯顿医疗补助服务产前诊所的黑人孕妇提供的 131 份匿名尿液样本。我们分析了尿液样本中的 15 种金属，包括镉 (Cd)、砷 (As)、铅 (Pb) 和镍 (Ni)，以及肌酸酐和可替宁。我们发现，本研究中黑人孕妇的锌 (Zn)、硒 (Se) 和铝 (Al) 的中位浓度比一组受过良好教育的非西班牙裔白人怀孕计划者报告的水平高 1.5 至 3 倍。与美国成年女性全国代表性样本相比，我们还观察到尿液中镉和锑 (Sb) 的水平升高。根据探索性因素分析的结果，该人群中金属暴露的潜在来源可能来自家庭环境，或者是由于饮食、工业和自然资源或交通。
The objective of this study was to characterize exposures to metals using biological samples collected on socioeconomically disadvantaged black pregnant women. We obtained 131 anonymous urine samples provided by black pregnant women visiting a Medicaid-serving prenatal clinic in Houston, TX, from March 27, 2017 to April 11, 2017. We analyzed urine samples for 15 metals including cadmium (Cd), arsenic (As), lead (Pb), and nickel (Ni) and for creatinine and cotinine. We found that median concentrations of zinc (Zn), selenium (Se), and aluminum (Al) among black pregnant women in this study were 1.5 to 3 times higher than levels reported among a cohort of well-educated non-Hispanic white pregnancy planners. We also observed elevated levels of urinary Cd and antimony (Sb) as compared with those reported for a nationally representative sample of adult women in the USA. Based on the results of an exploratory factor analysis, potential sources of metal exposures in this population may arise in home environments or be due to diet, industrial and natural sources, or traffic.