Two-year Follow-up of Volumetric-modulated Arc Therapy for Treating Internal Mammary Nodes in Locally Advanced Breast Cancer
Two-year Follow-up of Volumetric-modulated Arc Therapy for Treating Internal Mammary Nodes in Locally Advanced Breast Cancer
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DOI：
10.21873/anticanres.11047
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发表时间：
2016-09-01
影响因子：
2
通讯作者：
Lee, Jihae
中科院分区：
文献类型：
--
作者：
Kim, Yi-Jun;Kim, Kyubo;Lee, Jihae
背景/目的：我们评估了体积调节电弧疗法（VMAT）治疗局部晚期乳腺癌患者内乳腺淋巴结（IMNs）的剂量学和临床结果。患者和方法：分析2012年7月至2013年12月31例III期乳腺癌患者术后放疗包括VMAT的IMN野的治疗结果。结果：中位随访时间为25.2个月。VMAT表现出良好的均匀性和提高的一致性。2级及以上肺毒性发生率为3.2%，未观察到心脏毒性。无局部复发。结论：VMAT治疗局部晚期乳腺癌包括IMN领域是安全的。
Background/Aim: We evaluated dosimetric and clinical results of volumetric-modulated arc therapy (VMAT) treating internal mammary nodes (IMNs) in patients with locally advanced breast cancer. Patients and Methods: Between July 2012 and December 2013, treatment outcomes of 31 patients with stage III breast cancer treated with postoperative radiotherapy including the IMN field using VMAT were analyzed. Results: The median follow-up was 25.2 months. VMAT showed good homogeneity and improved conformity. The incidence of lung toxicity of grade 2 or more was 3.2%, and cardiac toxicity was not observed. No patient developed local recurrence. Conclusion: VMAT appears safe for the treatment of locally advanced breast cancer including the IMN field.