Computational Methods for Fluid-Structure Interaction Simulation of Heart Valves in Patient-Specific Left Heart Anatomies
Computational Methods for Fluid-Structure Interaction Simulation of Heart Valves in Patient-Specific Left Heart Anatomies
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DOI：
10.3390/fluids7030094
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发表时间：
2022-03
期刊：
影响因子：
1.9
通讯作者：
T. Le;M. Usta;C. Aidun;A. Yoganathan;F. Sotiropoulos
中科院分区：
文献类型：
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作者：
T. Le;M. Usta;C. Aidun;A. Yoganathan;F. Sotiropoulos
鉴于人类左心解剖和瓣膜结构的复杂性，天然瓣膜和人工瓣膜的流固耦合（FSI）模拟对数值方法提出了重大挑战。在这篇综述中，系统地考虑了患者特定左心心脏瓣膜流体和结构求解器的最新数值进展，强调了血流和瓣膜表面的数值处理，这是精确模拟的最关键方面。血流动力学的数值方法在连续和离散（粒子）方法下都被考虑。还回顾了主动脉/二尖瓣结构动力学的数值处理以及固体Ω和流体域Ωf之间的FSI耦合方法。还讨论了未来针对更先进的患者特定模拟的工作，包括体内测量中高保真模拟的融合以及基于数据分析和机器学习技术的基于物理的数字孪生。
Given the complexity of human left heart anatomy and valvular structures, the fluid–structure interaction (FSI) simulation of native and prosthetic valves poses a significant challenge for numerical methods. In this review, recent numerical advancements for both fluid and structural solvers for heart valves in patient-specific left hearts are systematically considered, emphasizing the numerical treatments of blood flow and valve surfaces, which are the most critical aspects for accurate simulations. Numerical methods for hemodynamics are considered under both the continuum and discrete (particle) approaches. The numerical treatments for the structural dynamics of aortic/mitral valves and FSI coupling methods between the solid Ωs and fluid domain Ωf are also reviewed. Future work toward more advanced patient-specific simulations is also discussed, including the fusion of high-fidelity simulation within vivo measurements and physics-based digital twining based on data analytics and machine learning techniques.