The associations between psychopathology and being overweight:: a 20-year prospective study
The associations between psychopathology and being overweight:: a 20-year prospective study
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DOI：
10.1017/s0033291703001697
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发表时间：
2004-08-01
影响因子：
6.9
通讯作者：
Angst, J
中科院分区：
文献类型：
--
作者：
Hasler, G;Pine, DS;Angst, J
背景精神疾病和超重是主要的健康问题，发病率越来越高。本研究的目的是检验这一假设，即超重与一系列精神疾病有关，包括轻微和非典型抑郁症，暴饮暴食和攻击性。对19至40岁的年轻人（n = 591）进行了前瞻性社区队列研究。信息来自六个随后的半结构化诊断访谈进行的专业人士超过二十年。结果是超重[体重指数（BMI）> 25]和20 - 40岁之间的平均年体重变化（BMI斜率）。18.9%的参与者被归类为超重。超重被证明是一个稳定的特征：77.7%的受试者在每次采访中都被分配到相同的体重级别。非典型抑郁症和暴饮暴食与体重增加和超重呈正相关，而与攻击性行为（攻击性人格特征，反社会）相关的精神疾病与超重呈正相关，但与体重变化率无关。广泛性焦虑症与超重呈负相关。在控制了物质使用、体力活动水平、人口统计学变量和体重问题家族史后，这些结果仍然存在。这项研究表明，与进食有关的和攻击性的精神病理学与超重之间存在相对较强的关联。鉴于这些疾病的高患病率，这项研究鼓励进一步研究精神病理学超重协会的因果关系，这可能会为重大健康问题提供新的预防方法。
Background. Psychiatric disorders and being overweight are major health problems with increasing prevalence. The purpose of this study was to test the hypothesis that being overweight is associated with a range of psychiatric conditions including minor and atypical depressive disorders, binge eating, and aggression.Method. Prospective community-based cohort study of young adults (n = 591) followed between ages 19 and 40. Information derived from six subsequent semi-structured diagnostic interviews conducted by professionals over twenty years. Outcomes were being overweight [body-mass index (BMI) > 25] and average yearly weight change between ages 20 and 40 (BMI slope).Results. 18.9% of the participants were classified as being overweight. Being overweight turned out to be a stable trait: 77.7% of subjects were assigned to the same weight class at each interview. Atypical depression and binge eating were positively associated with both, increased weight gain and being overweight, while psychiatric conditions associated with aggressive behaviors (aggressive personality traits, sociopathy) were positively associated with being overweight, but were not related to the rate of weight change. Generalized anxiety disorder was negatively associated with overweight. These results persisted after controlling for substance use, levels of physical activity, demographic variables and family history of weight problems.Conclusions. This study shows relatively strong associations between eating-related and aggressive psychopathology and being overweight. Given the high prevalence rates of these conditions, this study encourages further research on the causality of psychopathology-overweight associations that might provide insight on novel preventive approaches for major health problems.