Embryonic expression pattern of the murine figf gene, a growth factor belonging to platelet-derived growth factor vascular endothelial growth factor family
Embryonic expression pattern of the murine figf gene, a growth factor belonging to platelet-derived growth factor vascular endothelial growth factor family
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DOI：
10.1016/s0925-4773(98)00049-5
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发表时间：
1998-05-01
影响因子：
2.6
通讯作者：
Simeone, A
中科院分区：
文献类型：
--
作者：
Avantaggiato, V;Orlandini, M;Simeone, A
组织器官的形态发生、生长和分化需要信号分子、其受体和转录控制系统介导的细胞相互作用。c-fos诱导生长因子（figf）是血小板衍生生长因子/血管内皮生长因子（PDGF/VEGF）家族的新分泌成员，对成纤维细胞具有促有丝分裂活性。我们研究了小鼠胚胎发育过程中figf的表达。在几种身体结构和器官如肢芽、听神经节、牙齿、心脏、垂体前叶以及肺和肾间充质、肝脏、真皮和脊柱骨膜中检测到具有动态模式的FIGF表达。(C)1998爱思唯尔科学爱尔兰有限公司保留所有权利。
Morphogenesis, growth and differentiation of tissues acid organs require cell interactions mediated by signal molecules, their receptors and transcriptional control systems. c-fos-induced growth factor (figf) is a new secreted member of the platelet-derived growth factor/ vascular endothelial growth factor (PDGF/VEGF) family with mitogenic activity on fibroblasts. Here we studied figf expression during murine embryonic development. figf expression was detected with a dynamic pattern in several body structures and organs such as limb buds, acoustic ganglion, teeth, heart, anterior pituitary as well as lung and kidney mesenchyme, liver, derma, and periosteum of the vertebral column. (C) 1998 Elsevier Science Ireland Ltd. All rights reserved.