BAS1:: A gene regulating brassinosteroid levels and light responsiveness in Arabidopsis
BAS1:: A gene regulating brassinosteroid levels and light responsiveness in Arabidopsis
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DOI：
10.1073/pnas.96.26.15316
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发表时间：
1999-12-21
影响因子：
11.1
通讯作者：
Chory, J
中科院分区：
文献类型：
--
作者：
Neff, MM;Nguyen, SM;Chory, J
拟南芥bas1-D突变抑制由光感受器光敏色素B(PhyB)突变引起的长下胚轴表型，bas1-D PhyB-4双突变体的成体表型模仿油菜素类固醇生物合成和反应突变体的表型。在饲养实验中，BAS1-D PhyB-4降低了油菜素类固醇的水平，并积累了26-羟基油菜素内酯。突变表型的基础是细胞色素P450(CYP72B1)的增强表达，bas1-D抑制PhyB零等位基因，但不抑制PhyA零突变，并部分抑制隐色素零突变。BAS降低的苗木？BAS1以光依赖的方式对油菜素类固醇类化合物高反应，并在各种条件下表现出对光的敏感性降低，因此，BAS1是多个光感受器系统和油菜素类固醇信号转导之间的控制点之一。
The Arabidopsis bas1-D mutation suppresses the long hypocotyl phenotype caused by mutations in the photoreceptor phytochrome B (phyB), The adult phenotype of bas1-D phyB-4 double mutants mimics that of brassinosteroid biosynthetic: and response mutants. bas1-D phyB-4 has reduced levels of brassinosteroids and accumulates 26-hydroxybrassinolide in feeding experiments. The basis for the mutant phenotype is the enhanced expression of a cytochrome P450 (CYP72B1), bas1-D suppresses a phyB-null allele, but not a phyA-null mutation, and partially suppresses a cryptochrome-null mutation. Seedlings with reduced BAS? expression are hyperresponsive to brassinosteroids in a light-dependent manner and display reduced sensitivity to light under a variety of conditions, Thus, BAS1 represents one of the control points between multiple photoreceptor systems and brassinosteroid signal transduction.