Dimethyl 5-acetyl-1-hy-droxy-4-methyl-1H-pyrrole-2,3-di-carboxyl-ate, an oxidation-resistant N-hy-droxy-pyrrole.
Dimethyl 5-acetyl-1-hy-droxy-4-methyl-1H-pyrrole-2,3-di-carboxyl-ate, an oxidation-resistant N-hy-droxy-pyrrole.
复制标题
5-乙酰基-1-羟基-4-甲基-1H-吡咯-2,3-二羧酸二甲酯，一种抗氧化的 N-羟基吡咯。
DOI：
10.1107/s1600536813034466
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发表时间：
2014
期刊：
影响因子：
--
通讯作者：
Kao,JosephPY
中科院分区：
文献类型：
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作者：
Rosen,GeraldM;Muralidharan,Sukumaran;Zavalij,PeterY;Kao,JosephPY
The title compound, C11H13NO6, exhibits an intramolecular O–H⋯O=C hydrogen bond between the N-hydroxyl H atom and carbonyl O atom of the neighboring acetyl group. This finding contradicts a previously published model in which the hydrogen bond was postulated to occur with the neighboring carbomethoxy group. This relatively strong hydrogen bond [O—H⋯O: D = 2.5583 (11) Å and θ = 152°] may underlie the resistance of the title compound to oxidation into the corresponding nitroxide.
