Zinc-finger transcription factor Odd-Skipped related 2 is one of the regulators in osteoblast proliferation and bone formation
Zinc-finger transcription factor Odd-Skipped related 2 is one of the regulators in osteoblast proliferation and bone formation
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DOI：
10.1359/jbmr.070602
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发表时间：
2007-09-01
影响因子：
6.2
通讯作者：
Amano, Atsuo
中科院分区：
文献类型：
--
作者：
Kawai, Shinji;Yamauchi, Masashi;Amano, Atsuo
我们报告说，Osr2是成骨细胞功能的调节器之一，因为显性负Osr2转基因小鼠表现出成骨细胞活性下降，并在颅骨和胫骨组织矿化延迟。我们的研究结果表明，Osr2的功能在成骨细胞增殖的调节。
We report that Osr2 is one of the regulators of osteoblast function, because dominant-negative Osr2 transgenic mice exhibited decreased osteoblast activity and delayed mineralization in calvarial and tibial bone tissues. Our results indicate that Osr2 functions in regulation of osteoblast proliferation.