pH-Induced Shape-Memory Polymers
pH-Induced Shape-Memory Polymers
复制标题
pH 诱导的形状记忆聚合物
DOI：
10.1002/marc.201200153
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发表时间：
2012-06-27
影响因子：
4.6
通讯作者：
Zhang, Sheng
中科院分区：
文献类型：
--
作者：
Han, Xiao-Juan;Dong, Zhen-Qiang;Zhang, Sheng
通过β-环糊精修饰的海藻酸钠（β-CD-Alg）和二乙烯三胺修饰的海藻酸钠（DETA-Alg）的交联，制备了一种pH敏感的形状记忆聚合物（SMP）：pH可逆的β-CD-DETA包合物作为可逆相，交联的海藻酸钠链作为固定相。结果表明，该材料可以在pH 11.5下加工成我们需要的临时形状，并在pH 7下恢复到其初始形状。回收率和固定率分别为95.7 +/- 0.9%和94.8 +/-1.1%。该材料具有良好的生物相容性和可降解性。由于形状转变的pH值非常接近我们的体液，并且这种pH触发的形状记忆效应使用方便且安全，因此该材料具有很高的医学应用潜力。
A novel pH sensitive shape-memory polymer (SMP) is prepared by cross-linking the beta-cyclodextrin modified alginate (beta-CD-Alg) and diethylenetriamine modified alginate (DETA-Alg): The pH reversible beta-CD-DETA inclusion complexes serve as a reversible phase, and the cross-linked alginate chains serve as a fixing phase. It is shown that this material can be processed into temporary shape as we needs at pH 11.5 and recover to its initial shape at pH 7. The recovery ratio and the fixity ratio were 95.7 +/- 0.9% and 94.8 +/- 1.1%, respectively. Furthermore, this material showed good degradability and biocompatibility. Because the shape transition pH value is quite close to that of our body fluid and this pH triggered shape-memory effect is convenient and safe to use, this material has a high potential for medical application.