Patient motion correction for dynamic cardiac PET: Current status and challenges.
Patient motion correction for dynamic cardiac PET: Current status and challenges.
复制标题
动态心脏 PET 的患者运动校正：现状和挑战。
DOI：
10.1007/s12350-018-01513-x
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发表时间：
2020
期刊：
影响因子：
--
通讯作者：
Liu,Chi
中科院分区：
文献类型：
--
作者：
Lu,Yihuan;Liu,Chi
For dynamic cardiac PET of quantifying myocardial blood flow (MBF), patient motion is a major factor that affects the ROI definition and absolute quantification accuracy. In a recent study, an 82rubidium (82Rb)-dynamic-tailored motion-correction framework has been proposed to address the voluntary body motion for all the dynamic frames, including both early and late phases. 1 This approach brings us one step closer to the practical and full motion correction for dynamic cardiac PET studies. In this editorial, we discussed the current status and limitations of motion-correction methods for dynamic cardiac PET, including the recent publication at JNC, and also pointed out the remaining challenges for future developments.PET myocardial perfusion imaging has been shown to improve the detection accuracy of coronary artery disease as compared to other non-invasive imaging modalities. 2 Many investigators, in the past two decades, have established methods for absolute quantification of MBF and myocardial flow reserve (MFR) 3 using dynamic PET, which is superior in diagnostic and prognostic value as compared to the conventional relative myocardial perfusion imaging. 4 A prerequisite of accurate quantification in dynamic PET requires appropriate corrections 5 to the original dynamic frame data. In additional to corrections for physical factors such as attenuation, scatter, randoms, and normalization, physiological factors such as patient motion also require correction. Patient motion in cardiac
