GOITER AND OTHER THYROID DISEASES IN TECUMSEH MICHIGAN
GOITER AND OTHER THYROID DISEASES IN TECUMSEH MICHIGAN
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DOI：
10.1001/jama.1965.03080160054014
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发表时间：
1965-01-01
影响因子：
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通讯作者：
KJELSBERG, MO
中科院分区：
文献类型：
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作者：
MATOVINOVIC, J;HAYNER, NS;KJELSBERG, MO
在对密歇根州社区88%人口的8641人进行初步检查期间，在124名男性（2.9%）和451名女性（10.2%）中观察到甲状腺肿大。甲状腺肿的发病率仍然过高，特别是在19岁以上的妇女中（15%），尽管纠正缺碘的措施已经实施了30多年。因此，地方性甲状腺肿仍然是预防医学的一个重要问题。学龄儿童的甲状腺肿患病率并不表明总人口的甲状腺肿患病率。碘预防在降低甲状腺肿发病率方面取得了很大成就，但加碘盐的消费仍然不足。在特库姆塞，在冬季的一个月里，购买供人食用的盐中只有62%加了碘，这一水平大大低于永久和全面预防甲状腺肿的合理目标。在这一人群中，甲状腺肿大者与无甲状腺肿大者在身高和体重上没有明显差异。胎次与甲状腺肿患病率之间没有明确的联系。平均蛋白结合碘水平测定年龄在20至79岁的人随机样本;值之间没有显着差异的性别或个体之间有和没有甲状腺肿。在这项初步调查中，甲状腺肿并没有被发现在兄弟姐妹或母亲和他们的孩子中共存，比预期的更频繁。
During initial examinations of 8641 persons representing 88% of the population of a Michigan community, thyroid enlargement was observed in 124 males (2.9%) and 451 females (10.2%). Goiter persists at an excessive frequency, especially among women over age 19 (15%), in spite of measures to correct iodine deficiency which have been in effect for over 30 years. Thus, endemic goiter remains an important problem in preventive medicine. Goiter prevalence in school children does not indicate goiter prevalence in the total population. Iodine prophylaxis has accomplished much in decreasing the prevalence of goiter, but the consumption of iodized salt remains inadequate. In Tecumseh, only 62% of salt purchased for human consumption during one winter month was iodized, a level considerably below the reasonable goal of permanent and general goiter prophylaxis. In this population, persons with goiter did not differ appreciably in height and weight from those without goiter. No definite associationbetweenparity and goiter prevalence couldbe demonstrated. Mean protein-bound iodine levels were determined in random samples of persons age 20 to 79 years of age; values did not differ significantly between the sexes or between individuals with and without goiter. In this initial survey, goiter was not found to coexist within sib ships or in mothers and their children more often than would have been expected by chance alone.